Measuring herpes zoster disease burden in São Paulo, Brazil: a clinico-epidemiological single-center study

Herpes zoster is characterized by acute neuritis and post-herpetic neuralgia. Currently, data concerning the zoster-associated impact on quality of life and healthcare resource utilization in Brazil are scarce. This study measured the zoster-associated burden in a Brazilian population. This was a pr...

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Published in:Clinics (São Paulo, Brazil) Brazil), 2018-01, Vol.73, p.e243-e243, Article e243
Main Authors: Toniolo-Neto, João, Psaradellis, Eliofotisti, Karellis, Angela, Rampakakis, Emmanouil, Rockett, Talita Y., Sampalis, John S., Johnson, Kelly D., Monsanto, Homero A., Acosta, Camilo J.
Format: Article
Language:English
Subjects:
Age Distribution
Aged
Brazil
Brazil - epidemiology
Cost of Illness
Female
Herpes Zoster
Herpes Zoster - epidemiology
Herpes Zoster - pathology
Humans
Male
MEDICINE, GENERAL & INTERNAL
Middle Aged
Neuralgia, Postherpetic - epidemiology
Observational Study
Original
Pain
Prospective Studies
Quality of Life
Severity of Illness Index
Sex Distribution
Sickness Impact Profile
Socioeconomic Factors
Surveys and Questionnaires
Time Factors
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Summary:Herpes zoster is characterized by acute neuritis and post-herpetic neuralgia. Currently, data concerning the zoster-associated impact on quality of life and healthcare resource utilization in Brazil are scarce. This study measured the zoster-associated burden in a Brazilian population. This was a prospective, observational, single-cohort study conducted in a primary hospital's emergency room in São Paulo, Brazil. Patients enrolled at various timepoints during a zoster episode were followed over 180 days. The Zoster Brief Pain Inventory and the Initial Zoster Impact Questionnaire assessed zoster-associated pain. The EuroQoL assessed the impact of herpes zoster and/or zoster-associated pain on quality of life. Healthcare resource utilization was assessed by patient-reported questionnaires. One-hundred forty-six zoster patients were enrolled [mean (SD) age of 69.9 (10.9) years]. Mean (SD) worst pain scores decreased from 5.3 (3.5) at baseline to 1.9 (3.0) 180 days following rash onset. Mean (SD) EuroQoL scores significantly decreased from 0.9 (0.2) before rash appearance to 0.7 (0.2) after rash onset (p
ISSN:1807-5932
1980-5322
1980-5322
DOI:10.6061/clinics/2018/e243