Seroprevalence and risk factors associated with Helicobacter pylori infection in blood donors in Salvador, Northeast-Brazil

Helicobacter pylori plays an important role in the etiology of peptic ulcer disease. Its prevalence appears to be higher in developing countries. We evaluated the seroprevalence of H. pylori and risk factors associated with infection in voluntary blood donors who attended the main blood center of th...

Full description

Saved in:
Bibliographic Details
Published in:The Brazilian journal of infectious diseases 2003-10, Vol.7 (5), p.339-345
Main Authors: Lyra, Andre C, Santana, Genoile, Santana, Nelam, Silvany-Neto, Anibal, Magalhães, Emilia, Pereira, Eduardo M, Mascarenhas, Ramiro, Lyra, Marcos C, Veiga, Andrea, Ferreira, Karina, Zaterka, Schilioma, Lyra, Luiz G
Format: Article
Language:English
Subjects:
Adult
Antibodies, Bacterial - blood
Blood Donors
Brazil
Brazil - epidemiology
Enzyme-Linked Immunosorbent Assay
Epidemiologic Methods
Female
H. pylori
Helicobacter Infections - blood
Helicobacter Infections - diagnosis
Helicobacter Infections - epidemiology
Helicobacter pylori - immunology
Humans
INFECTIOUS DISEASES
Male
risk factors
seroprevalence
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Helicobacter pylori plays an important role in the etiology of peptic ulcer disease. Its prevalence appears to be higher in developing countries. We evaluated the seroprevalence of H. pylori and risk factors associated with infection in voluntary blood donors who attended the main blood center of the city of Salvador, Brazil. The subjects responded to an epidemiological questionnaire, with information about sex, age, race, lifestyle, social-economic level indicators, and residence and hygiene conditions. Anti-H. pylori antibody was determined by ELISA (Cobas Core, Roche). Three hundred and seven subjects were included in the study. Anti-H. pylori antibody results were indeterminate in 33 individuals (10.8%), who were excluded from analysis. Among the remaining 274 subjects, 187 (68.2%) were anti-H. pylori positive. Based on multivariate logistic regression analysis three variables were found to be significantly associated with a higher prevalence of H. pylori infection: absence of plumbing in the residence during childhood, a history of rainwater invading the dwelling during childhood, and low ingestion of milk.
ISSN:1413-8670
1678-4391
1413-8670
DOI:10.1590/S1413-86702003000500009