Seroepidemiology of Toxoplasma gondii Among Pregnant Women Attending Antenatal Care in Northwest Ethiopia

Toxoplasmosis is a life-threatening disease in pregnant women, having social and economic impacts due to congenital toxoplasmosis. However, in Ethiopia, it is neglected zoonotic disease, which requires screening and identifying risk factors in pregnant women to plan a public health intervention. Thi...

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Bibliographic Details
Published in:Infection and drug resistance 2021, Vol.14, p.1295-1303
Main Authors: Adugna, Biyansa, Tarekegn, Zewdu Seyoum, Damtie, Debasu, Woldegebreal, Seleshe Nigatu, Raju, R P, Maru, Moges, Ayele, Abrham
Format: Article
Language:English
Subjects:
Age groups
Agglutination
Analysis
Animals
Cysts
Drinking water
Fetuses
Food
Genotypes
Hospitals
Infections
Laboratories
Latex
Meat
Medical research
Medical screening
Medicine, Experimental
northwest ethiopia
Original Research
Pathogens
Pregnancy
Pregnant women
Prenatal care
Public health
Questionnaires
Risk factors
Seroepidemiology
Serology
seropositivity
t. gondii
Toxoplasma gondii
Toxoplasmosis
Womens health
Zoonoses
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Summary:Toxoplasmosis is a life-threatening disease in pregnant women, having social and economic impacts due to congenital toxoplasmosis. However, in Ethiopia, it is neglected zoonotic disease, which requires screening and identifying risk factors in pregnant women to plan a public health intervention. This institutional-based cross-sectional study was employed from March to April 2019 to estimate the seropositivity and assess potential risk factors for among pregnant women attending antenatal care in four public hospitals in Northwest Ethiopia. Four hundred and one pregnant women were recruited to collect serum samples. antibodies were tested using Toxo-Latex slide agglutination test. Thus, the overall seropositivity for was found 70.8% (95% CI: 66.3-75.5). Multivariable logistic regression analysis showed that the average monthly income, occupational status, habits of handwashing practices after handling raw meat, water sources for drinking and agroclimatic situations revealed significant ( < 0.05) effects on seropositivity for in pregnant women. This survey showed high seropositivity for among pregnant women in Northwest Ethiopia. Therefore, further studies on bioassay, isolation and genotype of the pathogen are crucial. It also requires action to prevent and control the infection with in pregnant women, which poses a potential threat to a foetus.
ISSN:1178-6973
1178-6973
DOI:10.2147/IDR.S299106