Lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustion

The present study assessed a complex of biochemical parameters at the anaerobic threshold (AT) in untrained male Wistar rats with different times to exhaustion (Tex) from swimming. The first group of rats was randomly divided into six subgroups and subjected to a swimming test to exhaustion without...

Full description

Saved in:
Bibliographic Details
Published in:Physiological reports 2023-09, Vol.11 (17), p.e15801-n/a
Main Authors: Potolitsyna, Natalya, Parshukova, Olga, Vakhnina, Nadezhda, Alisultanova, Nadezhda, Kalikova, Lubov, Tretyakova, Anastasia, Chernykh, Alexey, Shadrina, Vera, Duryagina, Arina, Bojko, Evgeny
Format: Article
Language:English
Subjects:
Adaptation
Anaerobic threshold
Athletes
Biochemistry
Body weight
Catecholamines
Cross country skiing
Endurance
Exercise
exhaustion
Laboratory animals
lactate biochemical indices
Lactic acid
Metabolites
Nitric oxide
Original
Physical fitness
Physiology
rats
Swimming
swimming test
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by
cites cdi_FETCH-LOGICAL-c5211-d41c88c3706052604b925fd593926aab413cff6d8cb3a728c8d84bff5b62d5513
container_end_page n/a
container_issue 17
container_start_page e15801
container_title Physiological reports
container_volume 11
creator Potolitsyna, Natalya
Parshukova, Olga
Vakhnina, Nadezhda
Alisultanova, Nadezhda
Kalikova, Lubov
Tretyakova, Anastasia
Chernykh, Alexey
Shadrina, Vera
Duryagina, Arina
Bojko, Evgeny
description The present study assessed a complex of biochemical parameters at the anaerobic threshold (AT) in untrained male Wistar rats with different times to exhaustion (Tex) from swimming. The first group of rats was randomly divided into six subgroups and subjected to a swimming test to exhaustion without a load or with a load of 2%–10% of body weight (BW). In the first group, we established that for untrained rats, the load of 4% BW in the swimming to exhaustion test was optimal for endurance assessment in comparison with other loads. The second group of rats went through a preliminary test with swimming to exhaustion at 4% BW and was then divided into two subgroups: long swimming time (LST, Tex > 240 min) and short swimming time (SST, Tex 
doi_str_mv 10.14814/phy2.15801
format article
fullrecord <record><control><sourceid>proquest_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_aea34bc2f1444e2fb8ff7d24e7c71c60</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><doaj_id>oai_doaj_org_article_aea34bc2f1444e2fb8ff7d24e7c71c60</doaj_id><sourcerecordid>2865989767</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5211-d41c88c3706052604b925fd593926aab413cff6d8cb3a728c8d84bff5b62d5513</originalsourceid><addsrcrecordid>eNp9kk9rFDEYxoMgtqw9-QUCXgTZmv_JnESKtoUFPViop5DJn50sM5M1ybjdb9_pThHqwVPgeX_5Ed48ALzD6BIzhdmnfXckl5grhF-Bc4I4Xiss78_ARSk7hBBGlDaIvQFnVAohqaTnYNgYW031sHbZly71rkAzOphT72EKcIw1RwvTQ3QexhEOZs6zqQXufQ4pD3HcQgOrLxUeYu3gnFnvYDnE4TSrCfqHzkylxjS-Ba-D6Yu_eD5X4O7b159XN-vN9-vbqy-bteUE47Vj2CplqUQCcSIQaxvCg-MNbYgwpmWY2hCEU7alRhJllVOsDYG3gjjOMV2B28XrktnpfY6DyUedTNSnIOWtNrlG23ttvKGstSRgxpgnoVUhSEeYl1ZiK9Ds-ry49lM7eGf9WLPpX0hfTsbY6W36ozFiUuJGzYYPz4acfk_zpvQQi_V9b0afpqKJEpgiQpiY0ff_oLs05XHe1RPFG9XI-eNW4ONC2ZxKyT78fQ1G-lQF_VQFfarCTJOFPsTeH_-H6h83v8hy6RG2Trf8</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2865989767</pqid></control><display><type>article</type><title>Lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustion</title><source>Open Access: Wiley-Blackwell Open Access Journals</source><source>Publicly Available Content Database</source><source>PubMed Central</source><creator>Potolitsyna, Natalya ; Parshukova, Olga ; Vakhnina, Nadezhda ; Alisultanova, Nadezhda ; Kalikova, Lubov ; Tretyakova, Anastasia ; Chernykh, Alexey ; Shadrina, Vera ; Duryagina, Arina ; Bojko, Evgeny</creator><creatorcontrib>Potolitsyna, Natalya ; Parshukova, Olga ; Vakhnina, Nadezhda ; Alisultanova, Nadezhda ; Kalikova, Lubov ; Tretyakova, Anastasia ; Chernykh, Alexey ; Shadrina, Vera ; Duryagina, Arina ; Bojko, Evgeny</creatorcontrib><description>The present study assessed a complex of biochemical parameters at the anaerobic threshold (AT) in untrained male Wistar rats with different times to exhaustion (Tex) from swimming. The first group of rats was randomly divided into six subgroups and subjected to a swimming test to exhaustion without a load or with a load of 2%–10% of body weight (BW). In the first group, we established that for untrained rats, the load of 4% BW in the swimming to exhaustion test was optimal for endurance assessment in comparison with other loads. The second group of rats went through a preliminary test with swimming to exhaustion at 4% BW and was then divided into two subgroups: long swimming time (LST, Tex &gt; 240 min) and short swimming time (SST, Tex &lt; 90 min). All rats of the second group performed, for 6 days, an experimental training protocol: swimming for 20 min each day with weight increasing each day. We established that the AT was 3% BW in SST rats and 5% BW in LST rats. The AT shifted to the right on the lactate curve in LST rats. Also, at the AT in the LST rats, we found significantly lower levels of blood lactate, cortisol, and NO.</description><identifier>EISSN: 2051-817X</identifier><identifier>DOI: 10.14814/phy2.15801</identifier><identifier>PMID: 37667373</identifier><language>eng</language><publisher>Oxford: John Wiley &amp; Sons, Inc</publisher><subject>Adaptation ; Anaerobic threshold ; Athletes ; Biochemistry ; Body weight ; Catecholamines ; Cross country skiing ; Endurance ; Exercise ; exhaustion ; Laboratory animals ; lactate biochemical indices ; Lactic acid ; Metabolites ; Nitric oxide ; Original ; Physical fitness ; Physiology ; rats ; Swimming ; swimming test</subject><ispartof>Physiological reports, 2023-09, Vol.11 (17), p.e15801-n/a</ispartof><rights>2023 Institute of Physiology of Komi Science Center of the UB of the RAS. published by Wiley Periodicals LLC on behalf of The Physiological Society and the American Physiological Society.</rights><rights>2023. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c5211-d41c88c3706052604b925fd593926aab413cff6d8cb3a728c8d84bff5b62d5513</cites><orcidid>0000-0003-4804-6908 ; 0000-0002-8027-898X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2865989767/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2865989767?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,11562,25753,27924,27925,37012,37013,44590,46052,46476,53791,53793,75126</link.rule.ids></links><search><creatorcontrib>Potolitsyna, Natalya</creatorcontrib><creatorcontrib>Parshukova, Olga</creatorcontrib><creatorcontrib>Vakhnina, Nadezhda</creatorcontrib><creatorcontrib>Alisultanova, Nadezhda</creatorcontrib><creatorcontrib>Kalikova, Lubov</creatorcontrib><creatorcontrib>Tretyakova, Anastasia</creatorcontrib><creatorcontrib>Chernykh, Alexey</creatorcontrib><creatorcontrib>Shadrina, Vera</creatorcontrib><creatorcontrib>Duryagina, Arina</creatorcontrib><creatorcontrib>Bojko, Evgeny</creatorcontrib><title>Lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustion</title><title>Physiological reports</title><description>The present study assessed a complex of biochemical parameters at the anaerobic threshold (AT) in untrained male Wistar rats with different times to exhaustion (Tex) from swimming. The first group of rats was randomly divided into six subgroups and subjected to a swimming test to exhaustion without a load or with a load of 2%–10% of body weight (BW). In the first group, we established that for untrained rats, the load of 4% BW in the swimming to exhaustion test was optimal for endurance assessment in comparison with other loads. The second group of rats went through a preliminary test with swimming to exhaustion at 4% BW and was then divided into two subgroups: long swimming time (LST, Tex &gt; 240 min) and short swimming time (SST, Tex &lt; 90 min). All rats of the second group performed, for 6 days, an experimental training protocol: swimming for 20 min each day with weight increasing each day. We established that the AT was 3% BW in SST rats and 5% BW in LST rats. The AT shifted to the right on the lactate curve in LST rats. Also, at the AT in the LST rats, we found significantly lower levels of blood lactate, cortisol, and NO.</description><subject>Adaptation</subject><subject>Anaerobic threshold</subject><subject>Athletes</subject><subject>Biochemistry</subject><subject>Body weight</subject><subject>Catecholamines</subject><subject>Cross country skiing</subject><subject>Endurance</subject><subject>Exercise</subject><subject>exhaustion</subject><subject>Laboratory animals</subject><subject>lactate biochemical indices</subject><subject>Lactic acid</subject><subject>Metabolites</subject><subject>Nitric oxide</subject><subject>Original</subject><subject>Physical fitness</subject><subject>Physiology</subject><subject>rats</subject><subject>Swimming</subject><subject>swimming test</subject><issn>2051-817X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNp9kk9rFDEYxoMgtqw9-QUCXgTZmv_JnESKtoUFPViop5DJn50sM5M1ybjdb9_pThHqwVPgeX_5Ed48ALzD6BIzhdmnfXckl5grhF-Bc4I4Xiss78_ARSk7hBBGlDaIvQFnVAohqaTnYNgYW031sHbZly71rkAzOphT72EKcIw1RwvTQ3QexhEOZs6zqQXufQ4pD3HcQgOrLxUeYu3gnFnvYDnE4TSrCfqHzkylxjS-Ba-D6Yu_eD5X4O7b159XN-vN9-vbqy-bteUE47Vj2CplqUQCcSIQaxvCg-MNbYgwpmWY2hCEU7alRhJllVOsDYG3gjjOMV2B28XrktnpfY6DyUedTNSnIOWtNrlG23ttvKGstSRgxpgnoVUhSEeYl1ZiK9Ds-ry49lM7eGf9WLPpX0hfTsbY6W36ozFiUuJGzYYPz4acfk_zpvQQi_V9b0afpqKJEpgiQpiY0ff_oLs05XHe1RPFG9XI-eNW4ONC2ZxKyT78fQ1G-lQF_VQFfarCTJOFPsTeH_-H6h83v8hy6RG2Trf8</recordid><startdate>202309</startdate><enddate>202309</enddate><creator>Potolitsyna, Natalya</creator><creator>Parshukova, Olga</creator><creator>Vakhnina, Nadezhda</creator><creator>Alisultanova, Nadezhda</creator><creator>Kalikova, Lubov</creator><creator>Tretyakova, Anastasia</creator><creator>Chernykh, Alexey</creator><creator>Shadrina, Vera</creator><creator>Duryagina, Arina</creator><creator>Bojko, Evgeny</creator><general>John Wiley &amp; Sons, Inc</general><general>John Wiley and Sons Inc</general><general>Wiley</general><scope>24P</scope><scope>WIN</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7T5</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M7P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0003-4804-6908</orcidid><orcidid>https://orcid.org/0000-0002-8027-898X</orcidid></search><sort><creationdate>202309</creationdate><title>Lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustion</title><author>Potolitsyna, Natalya ; Parshukova, Olga ; Vakhnina, Nadezhda ; Alisultanova, Nadezhda ; Kalikova, Lubov ; Tretyakova, Anastasia ; Chernykh, Alexey ; Shadrina, Vera ; Duryagina, Arina ; Bojko, Evgeny</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5211-d41c88c3706052604b925fd593926aab413cff6d8cb3a728c8d84bff5b62d5513</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Adaptation</topic><topic>Anaerobic threshold</topic><topic>Athletes</topic><topic>Biochemistry</topic><topic>Body weight</topic><topic>Catecholamines</topic><topic>Cross country skiing</topic><topic>Endurance</topic><topic>Exercise</topic><topic>exhaustion</topic><topic>Laboratory animals</topic><topic>lactate biochemical indices</topic><topic>Lactic acid</topic><topic>Metabolites</topic><topic>Nitric oxide</topic><topic>Original</topic><topic>Physical fitness</topic><topic>Physiology</topic><topic>rats</topic><topic>Swimming</topic><topic>swimming test</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Potolitsyna, Natalya</creatorcontrib><creatorcontrib>Parshukova, Olga</creatorcontrib><creatorcontrib>Vakhnina, Nadezhda</creatorcontrib><creatorcontrib>Alisultanova, Nadezhda</creatorcontrib><creatorcontrib>Kalikova, Lubov</creatorcontrib><creatorcontrib>Tretyakova, Anastasia</creatorcontrib><creatorcontrib>Chernykh, Alexey</creatorcontrib><creatorcontrib>Shadrina, Vera</creatorcontrib><creatorcontrib>Duryagina, Arina</creatorcontrib><creatorcontrib>Bojko, Evgeny</creatorcontrib><collection>Open Access: Wiley-Blackwell Open Access Journals</collection><collection>Wiley Online Library</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium &amp; Calcified Tissue Abstracts</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>ProQuest Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Biological Sciences</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Biological Science Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>Directory of Open Access Journals</collection><jtitle>Physiological reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Potolitsyna, Natalya</au><au>Parshukova, Olga</au><au>Vakhnina, Nadezhda</au><au>Alisultanova, Nadezhda</au><au>Kalikova, Lubov</au><au>Tretyakova, Anastasia</au><au>Chernykh, Alexey</au><au>Shadrina, Vera</au><au>Duryagina, Arina</au><au>Bojko, Evgeny</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustion</atitle><jtitle>Physiological reports</jtitle><date>2023-09</date><risdate>2023</risdate><volume>11</volume><issue>17</issue><spage>e15801</spage><epage>n/a</epage><pages>e15801-n/a</pages><eissn>2051-817X</eissn><abstract>The present study assessed a complex of biochemical parameters at the anaerobic threshold (AT) in untrained male Wistar rats with different times to exhaustion (Tex) from swimming. The first group of rats was randomly divided into six subgroups and subjected to a swimming test to exhaustion without a load or with a load of 2%–10% of body weight (BW). In the first group, we established that for untrained rats, the load of 4% BW in the swimming to exhaustion test was optimal for endurance assessment in comparison with other loads. The second group of rats went through a preliminary test with swimming to exhaustion at 4% BW and was then divided into two subgroups: long swimming time (LST, Tex &gt; 240 min) and short swimming time (SST, Tex &lt; 90 min). All rats of the second group performed, for 6 days, an experimental training protocol: swimming for 20 min each day with weight increasing each day. We established that the AT was 3% BW in SST rats and 5% BW in LST rats. The AT shifted to the right on the lactate curve in LST rats. Also, at the AT in the LST rats, we found significantly lower levels of blood lactate, cortisol, and NO.</abstract><cop>Oxford</cop><pub>John Wiley &amp; Sons, Inc</pub><pmid>37667373</pmid><doi>10.14814/phy2.15801</doi><tpages>12</tpages><orcidid>https://orcid.org/0000-0003-4804-6908</orcidid><orcidid>https://orcid.org/0000-0002-8027-898X</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier EISSN: 2051-817X
ispartof Physiological reports, 2023-09, Vol.11 (17), p.e15801-n/a
issn 2051-817X
language eng
recordid cdi_doaj_primary_oai_doaj_org_article_aea34bc2f1444e2fb8ff7d24e7c71c60
source Open Access: Wiley-Blackwell Open Access Journals; Publicly Available Content Database; PubMed Central
subjects Adaptation
Anaerobic threshold
Athletes
Biochemistry
Body weight
Catecholamines
Cross country skiing
Endurance
Exercise
exhaustion
Laboratory animals
lactate biochemical indices
Lactic acid
Metabolites
Nitric oxide
Original
Physical fitness
Physiology
rats
Swimming
swimming test
title Lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustion
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-23T09%3A04%3A08IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Lactate%20thresholds%20and%20role%20of%20nitric%20oxide%20in%20male%20rats%20performing%20a%20test%20with%20forced%20swimming%20to%20exhaustion&rft.jtitle=Physiological%20reports&rft.au=Potolitsyna,%20Natalya&rft.date=2023-09&rft.volume=11&rft.issue=17&rft.spage=e15801&rft.epage=n/a&rft.pages=e15801-n/a&rft.eissn=2051-817X&rft_id=info:doi/10.14814/phy2.15801&rft_dat=%3Cproquest_doaj_%3E2865989767%3C/proquest_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c5211-d41c88c3706052604b925fd593926aab413cff6d8cb3a728c8d84bff5b62d5513%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2865989767&rft_id=info:pmid/37667373&rfr_iscdi=true