Intention to get naloxone among patients prescribed opioids for chronic pain

Prescription opioids have been increasingly prescribed for chronic pain while the opioid-related death rates grow. Naloxone, an opioid antagonist, is increasingly recommended in these patients, yet there is limited research that investigates the intention to get naloxone. This study aimed to investi...

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Bibliographic Details
Published in:Harm reduction journal 2022-09, Vol.19 (1), p.104-11, Article 104
Main Authors: Huang, Yinan, Lyu, Ning, Gohil, Shrey, Bapat, Shweta, Essien, E James, Thornton, J Douglas
Format: Article
Language:English
Subjects:
Adult
Analgesics, Opioid - therapeutic use
Attitudes
Behavior
Care and treatment
Chronic pain
Chronic Pain - chemically induced
Chronic Pain - complications
Chronic Pain - drug therapy
Complications and side effects
Cross-Sectional Studies
Demographics
Dosage and administration
Drug overdose
Drug Overdose - drug therapy
Drug utilization
Empirical analysis
Female
Harm reduction
Humans
Intention
Male
Medication abuse
Medication safety
Methods
Naloxone
Naloxone - therapeutic use
Narcotic Antagonists - therapeutic use
Narcotics
Norms
Opioids
Overdose
Pain
Patients
Population studies
Prevention
Regression analysis
Risk analysis
Risk factors
Surveys
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Summary:Prescription opioids have been increasingly prescribed for chronic pain while the opioid-related death rates grow. Naloxone, an opioid antagonist, is increasingly recommended in these patients, yet there is limited research that investigates the intention to get naloxone. This study aimed to investigate intention toward getting naloxone in patients prescribed opioids for chronic pain and to assess the predictive utility of the theory of reasoned action (TRA) constructs in explaining intention to get naloxone. This was a cross-sectional study of a panel of U.S. adult patients prescribed opioids for chronic pain using a Qualtrics survey. These patients participated in the study during February to March 2020. The online internet survey assessed the main outcome of intention to get naloxone and constructs of TRA (attitudes and subjective norms); additional measures assessed the characteristics of patients' opioid overdose risk factors, knowledge of naloxone, and their demographics. The relationship between TRA constructs, namely, attitudes and subjective norms, and the intention variable was examined using logistic regression analyses with the intention outcome contrasted as follows: high intention (scores ≥ 5) and non-high intention (scores 
ISSN:1477-7517
1477-7517
DOI:10.1186/s12954-022-00687-5