A study on atypical Kashin-Beck disease: an endemic ankle arthritis

To study the epidemiological characteristics of atypical Kashin-Beck disease cases without characteristic hand lesions such as interphalangeal joint enlargement and brachydactyly and the characteristics of ankle joint lesions. We investigated Kashin-Beck in the endemic villages in Heilongjiang Provi...

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Bibliographic Details
Published in:Journal of orthopaedic surgery and research 2023-05, Vol.18 (1), p.328-328, Article 328
Main Authors: Qi, Fang, Cui, Si-Lu, Zhang, Bing, Li, Hao-Nan, Yu, Jun
Format: Article
Language:English
Subjects:
Adult
Ankle
Ankle changes
Ankle Joint
Arthritis
Atypical Kashin–Beck disease
Brachydactyly
Cartilage
Correspondence
Disease
Dwarfism
Epidemiology
Hand
Humans
Kashin-Beck Disease - diagnosis
Kashin–Beck disease
Lesions
Medical research
Medicine, Experimental
Orthopedics
Osteoarthritis - epidemiology
Pathogenesis
Patients
Questionnaires
Statistical analysis
Surveys
Towns
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Summary:To study the epidemiological characteristics of atypical Kashin-Beck disease cases without characteristic hand lesions such as interphalangeal joint enlargement and brachydactyly and the characteristics of ankle joint lesions. We investigated Kashin-Beck in the endemic villages in Heilongjiang Province. The patients were judged according to the "Diagnosis of Kashin-Beck Disease" (WS/T 207-2010). The severity of foot lesions was judged based on the changes of X-ray images. Residents of non-Kashin-Beck disease area were selected as normal controls in Jilin Province. A total of 119 residents over 40 years old were surveyed in a natural village in the non-endemic area. A total of 1190 residents over 40 years old were surveyed in 38 endemic areas of Kashin-Beck disease. A total of 710 patients with Kashin-Beck disease were detected, including 245 patients with grade I, 175 patients with grade II, 25 patients with grade III, and 265 atypical patients. Among all investigated patients, 92.0% (653/710) had ankle joint changes, and it was 80.0% (196/245) in grade I patients and 95.4% (167/175) in grade II. Varying degrees of ankle joint changes were found in both grade III and atypical patients. The grade of Kashin-Beck disease was correlated with the degree of ankle joint change (P 
ISSN:1749-799X
1749-799X
DOI:10.1186/s13018-023-03633-8