Significant Low-Dimensional Spectral-Temporal Features for Seizure Detection

• Published in: IEEE transactions on neural systems and rehabilitation engineering 2022, Vol.30, p.668-677
• Main Authors: Yan, Xucun, Yang, Dongping, Lin, Zihuai, Vucetic, Branka
• Format: Article
• Language: English
• Subjects: Adult; Algorithms; Artificial neural networks; Attention deficit hyperactivity disorder; Child; Computational neuroscience; Continuous wavelet transforms; convolutional neural network (CNN); Datasets; Discrete wavelet transforms; EEG; Electrodes; electroencephalogram (EEG); Electroencephalography; Electroencephalography - methods; Epilepsy - diagnosis; Feature extraction; Humans; Hyperactivity; mean-standard deviation of wavelet transform coefficient (MS-WTC); Neural networks; Reproducibility of Results; Seizure detection; Seizures; Seizures - diagnosis; Signal Processing, Computer-Assisted; Spectra; Stochasticity; Temporal variations; Time-frequency analysis; Transforms; Wavelet transforms
• ISSN: 1534-4320; 1558-0210
• DOI: 10.1109/TNSRE.2022.3156931

Absence seizure as a generalized onset seizure, simultaneously spreading seizure to both sides of the brain, involves around ten-second sudden lapses of consciousness. It common occurs in children than adults, which affects living quality even threats lives. Absence seizure can be confused with inattentive attention-deficit hyperactivity disorder since both have similar symptoms, such as inattention and daze. Therefore, it is necessary to detect absence seizure onset. However, seizure onset detection in electroencephalography (EEG) signals is a challenging task due to the non-stereotyped seizure activities as well as their stochastic and non-stationary characteristics in nature. Joint spectral-temporal features are believed to contain sufficient and powerful feature information for absence seizure detection. However, the resulting high-dimensional features involve redundant information and require heavy computational load. Here, we discover significant low-dimensional spectral-temporal features in terms of mean-standard deviation of wavelet transform coefficient (MS-WTC), based on which a novel absence seizure detection framework is developed. The EEG signals are transformed into the spectral-temporal domain, with their low-dimensional features fed into a convolutional neural network. Superior detection performance is achieved on the widely-used benchmark dataset as well as a clinical dataset from the Chinese 301 Hospital. For the former, seven classification tasks were evaluated with the accuracy from 99.8% to 100.0%, while for the latter, the method achieved a mean accuracy of 94.7%, overwhelming other methods with low-dimensional temporal and spectral features. Experimental results on two seizure datasets demonstrate reliability, efficiency and stability of our proposed MS-WTC method, validating the significance of the extracted low-dimensional spectral-temporal features.