Effect of multimodal exercise training on physical fitness indices, cognitive status, and depressive symptoms in Alzheimer's disease

In Alzheimer's disease (AD) patients, low levels of physical fitness (PF) and cognitive status are associated with high rates of depression. However, this condition can be improved through physical training. The aim of the present study was to investigate the effect of multimodal exercise train...

Full description

Saved in:
Bibliographic Details
Published in:Dementia & neuropsychologia 2023, Vol.17, p.e20220008-e20220008
Main Authors: Haghighi, Amir Hossein, Barzoei, Masoud, Kakhak, Seyed Alireza Hosseini, Budini, Francesco, Shahrabadi, Hadi
Format: Article
Language:English
Subjects:
Alzheimer Disease
CLINICAL NEUROLOGY
Depression
Exercise
GERIATRICS & GERONTOLOGY
HEALTH CARE SCIENCES & SERVICES
MEDICINE, GENERAL & INTERNAL
NURSING
Original
Physical Fitness
PSYCHIATRY
PSYCHOLOGY
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In Alzheimer's disease (AD) patients, low levels of physical fitness (PF) and cognitive status are associated with high rates of depression. However, this condition can be improved through physical training. The aim of the present study was to investigate the effect of multimodal exercise training (MET) on aerobic endurance, muscular strength, agility, dynamic balance, cognitive status, and depressive symptoms in men with mild-to-moderate AD. A total of 25 elderly men with a diagnosis of mild-to-moderate AD were randomly categorized into an MET or a control group. The subjects in the MET group participated in a 12-week, three sessions per week MET program that included resistance, balance, and aerobic exercises. While the participants in the control group did not perform any regular exercise training during this period. Patients' cognitive status and depressive symptoms were assessed by Mini-Mental State Examination and the Geriatric Depression Scale-15 (GDS-15) questionnaires. PF indicators such as aerobic endurance, muscular strength, agility, and dynamic balance, as well as cognitive status and depressive symptoms, were taken from all the subjects before and after MET. The participants in the MET group improved handgrip, upper and lower body strength, agility, dynamic balance, and depressive symptoms (p0.05). MET is an effective strategy to improve muscular strength, agility, dynamic balance, and depressive symptoms in men with mild-to-moderate AD. It is recommended for AD patients to engage in this type of exercise to reduce AD complications.
ISSN:1980-5764
1980-5764
2764-4863
DOI:10.1590/1980-5764-DN-2022-0008