Anthropometry in Children with Transfusion-Dependent Beta-Thalassemia Major

ABSTRACT Objective: To determine the abnormal anthropometric findings among children diagnosed with and managed for transfusion-dependent beta-thalassemia major. Study Design: Cross-sectional study. Setting and Duration of Study: Department of Paediatric Medicine, Pak Emirates Military Hospital, Raw...

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Bibliographic Details
Published in:Pakistan Armed Forces medical journal 2023-12, Vol.73 (6), p.1565
Main Authors: Nisa, Noor Un, Farooq Ikram, Tahir, Muhammad
Format: Article
Language:English
Subjects:
Age
Anthropometry
Blood diseases
Blood transfusion
Blood transfusions
Care and treatment
Chelation therapy
Complications and side effects
Data analysis
Growth disorders
Hemoglobin
Life expectancy
Metabolism
Nutrition
Patients
Pediatrics
Puberty
Socio-demographic variables
Sociodemographics
Standard scores
Thalassemia
Weight
β-Thalassemia major
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Summary:ABSTRACT Objective: To determine the abnormal anthropometric findings among children diagnosed with and managed for transfusion-dependent beta-thalassemia major. Study Design: Cross-sectional study. Setting and Duration of Study: Department of Paediatric Medicine, Pak Emirates Military Hospital, Rawalpindi Pakistan, from Sep 2019 to Aug 2020. Methodology: This study involved 310 children of both genders aged 2 to 18 years presenting with beta-thalassemia Major receiving multiple blood transfusions. Anthropometric findings, including height and weight for age, were measured and plotted via World Health Organization-2007 growth charts in all the study participants. Relevant socio-demographic variables, including serum ferritin, were correlated with abnormal anthropometric findings among these children. Results: The mean age of the patients was 8.87±7.42 years. 170(54.8%) male and 140(45.2%) female patients were in the study group. Most of the children [218 (70.3%)] had any abnormal an-thropometric findings, either weight or height for age, while 92 (29.7%) had no anthropometric abnormality. Majority of the patients [198 (63.8%)] patients had stunted growth, while 170 (54.8%) were underweight. Longer duration of transfusion and raised serum ferritin levels had a statistically significant corre-lation with any anthropometric abnormality among the beta-thalassemia major patients (p-value
ISSN:0030-9648
2411-8842
DOI:10.51253/pafmj.v73i6.5814