The seminal fluid protein SFP-1 regulates mated hermaphrodite aging and fat metabolism in C. elegans

Across the evolutionary spectrum, sexual interactions can significantly influence the physiology and somatic aging in various species. In Caenorhabditis, male pheromones, sperm, and seminal fluid shorten the lifespan of hermaphrodites through different mechanisms. However, the specific male seminal...

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Bibliographic Details
Published in:The EMBO journal 2025-12, Vol.44 (23), p.7181-7210
Main Authors: Chen, Mingqing, Gong, Jianke
Format: Article
Language:English
Subjects:
Aging
Animals
Biomedical and Life Sciences
Caenorhabditis elegans - genetics
Caenorhabditis elegans - metabolism
Caenorhabditis elegans - physiology
Caenorhabditis elegans Proteins - genetics
Caenorhabditis elegans Proteins - metabolism
Cell Biology
DNA-Binding Proteins - genetics
DNA-Binding Proteins - metabolism
EMBO37
EMBO45
Female
Hermaphroditic Organisms - metabolism
Hermaphroditic Organisms - physiology
Life Sciences
Lipid Metabolism
Longevity
Male
Mating
Phospholipid Transfer Proteins - genetics
Phospholipid Transfer Proteins - metabolism
Seminal Fluid Protein
Seminal Plasma Proteins - genetics
Seminal Plasma Proteins - metabolism
Sexual Behavior, Animal
Transcription Factors - genetics
Transcription Factors - metabolism
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