Antimicrobial Potential of Microorganisms Isolated from the Bottom Sediments of Lake Baikal

Extremophilic microorganisms attract researchers by their unique characteristics, primarily antagonistic ones, acquired in the process of survival in extreme natural conditions. The antimicrobial potential of the metabolites of these microorganisms is quite broad, from the food industry to therapeut...

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Bibliographic Details
Published in:Antibiotics (Basel) 2021-07, Vol.10 (8), p.927
Main Authors: Babich, Olga, Shevchenko, Margarita, Ivanova, Svetlana, Pavsky, Valery, Zimina, Maria, Noskova, Svetlana, Anohova, Veronika, Chupakhin, Evgeny, Sukhikh, Stanislav
Format: Article
Language:English
Subjects:
Antiinfectives and antibacterials
Antimicrobial activity
Bacteria
Bacteriocins
Bottom sediments
Carbon
Chemical elements
Coastal zone
extremophilic microorganisms
Food industry
genetic identification
Growth conditions
Heterotrophic growth
Lake Baikal
Lake sediments
Lakes
Low molecular weights
Magnesium
Metabolites
Microbial mats
Microorganisms
Molecular weight
Morphology
Oceans
Oligopeptides
Peptides
Phylogenetics
Physiology
Potassium
Pseudomonas putida
Rivers
Salinity
Sediments
Sodium
Strains (organisms)
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Summary:Extremophilic microorganisms attract researchers by their unique characteristics, primarily antagonistic ones, acquired in the process of survival in extreme natural conditions. The antimicrobial potential of the metabolites of these microorganisms is quite broad, from the food industry to therapeutic drugs. Microbial mats of Lake Baikal are a source of unique and diverse microorganisms. The study aimed to evaluate the antimicrobial activity of bacterial strains isolated from the bottom sediments of the lake. Using heterotrophic growth conditions, seven bacterial strains were isolated from samples collected in several coastal zones of Lake Baikal. Thisstudy identified both widespread strains of the genera Pseudomonas and Bacillus and rare genera Micrococcus and Acinetobacterrepresentatives. Metabolites of five strains were found to have a broad spectrum of antimicrobial activity. Four large fractions of metabolites of the isolated strains wereidentified. Two peptides of the isolated fractions of metabolites (one is produced by microorganisms of all five isolated strains, another—only by Pseudomonas putida) are low molecular weight oligopeptides. These peptides were proved to be bacteriocins.
ISSN:2079-6382
2079-6382
DOI:10.3390/antibiotics10080927