Susceptibility results discrepancy analysis between NHSN Antibiotic Resistance (AR) Option and laboratory instrument data

Background: The NHSN Antibiotic Resistance (AR) Option can serve as a useful tool for tracking antibiotic-resistant infections and can aid in the development of inpatient antibiograms. We recently described the frequency of antibiotic suppression in NHSN AR Option data. In this analysis, we describe...

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Bibliographic Details
Published in:Antimicrobial stewardship & healthcare epidemiology : ASHE 2022-07, Vol.2 (S1), p.s66-s66
Main Authors: Ouedraogo, Youssoufou, Evans, Christopher, Muleta, Daniel, Wilson, Christopher
Format: Article
Language:English
Subjects:
Antibiotic resistance
Antibiotic Stewardship
Antibiotics
Drug resistance
E coli
Laboratories
Pathogens
Poster Presentation - Oral Presentation
Public health
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Summary:Background: The NHSN Antibiotic Resistance (AR) Option can serve as a useful tool for tracking antibiotic-resistant infections and can aid in the development of inpatient antibiograms. We recently described the frequency of antibiotic suppression in NHSN AR Option data. In this analysis, we describe the effects of suppression on practical uses of the NHSN AR Option, specifically selected agent antibiogram development, and detection of reportable conditions. Methods: Antibiotic susceptibility data were collected from the NHSN AR Option and commercial automated antimicrobial susceptibility testing instruments (cASTI) from 3 hospital networks. Data were obtained from January 1, 2017, to December 31, 2018. The clinical susceptibility data for third-generation cephalosporins and carbapenems against carbapenem-resistant Enterobacterales (CRE), Pseudomonas aeruginosa , and Acinetobacter baumannii were included. Susceptibility results were defined as suppressed when susceptibility results were observed from the laboratory instrument but not from NHSN data. For the overall percentage susceptibility estimation, isolates with
ISSN:2732-494X
2732-494X
DOI:10.1017/ash.2022.185