Management of intervenable factors to reduce vascular complications in patients with internal carotid artery occlusion treated by non-emergency endovascular treatment

• Published in: Frontiers in neurology 2024-03, Vol.15, p.1332940-1332940
• Main Authors: Wu, Guangyu, Nong, Yuxin, Hong, Shaorui, Wang, Shuo, Dai, Chengbo, He, Chizhong, Li, Changmao, Ma, Tengyun, Yang, Zhexian, Zhang, Bin, Gao, Yuyuan, Ma, Guixian
• Format: Article
• Language: English
• Subjects: glycosylated hemoglobin; internal carotid artery occlusion; non-emergency endovascular treatment; non-neurology guide wires; vascular complications
• ISSN: 1664-2295; 1664-2295
• DOI: 10.3389/fneur.2024.1332940

This study aims to identify risk factors for vascular complications during non-emergency endovascular treatment in patients with internal carotid artery occlusion (ICAO) and to propose potential interventions. A retrospective analysis of 92 patients with ICAO who received non-emergency endovascular treatment in our center from 1 January 2018 to 31 June 2023, was conducted. The correlation between intraoperative vascular complications and potential risk factors was studied, and interaction analysis was performed. Our findings revealed that the use of non-neurology guide wires to open vessels (adjusted OR: 4.1, 95%CI: 1.3-12.8;  = 0.014) and glycosylated hemoglobin (HbA1c) ≥ 6.5 mmol/L (adjusted OR: 3.2, 95%CI: 1.2-8.9;  = 0.023) was significantly associated with vascular complications in non-emergency endovascular treatment of ICAO patients. The restricted cubic spline (RCS) showed that the higher the HbA1c level, the higher the risk of vascular complications. The use of non-neurology guide wires for vessel opening during non-emergency endovascular treatment in patients with ICAO increases the risk of vascular complications. Preoperative assessment and management of HbA1c levels can reduce the incidence of intraoperative vascular complications.