Optimal LDL cholesterol levels in young and old patients with type 2 diabetes for secondary prevention of cardiovascular diseases are different

Objective Real-world-based population data about the optimal low-density lipoprotein cholesterol (LDL-C) level for preventing cardiovascular disease in very high-risk populations is scarce. Methods From 2009 to 2012, 26,922 people aged ≥ 40 years with type 2 diabetes mellitus (T2DM) who had a histor...

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Bibliographic Details
Published in:Endocrine Connections 2023-11, Vol.12 (11), p.1-10
Main Authors: Jeong, Chaiho, Kim, Bongseong, Kim, Jinyoung, Baek, Hansang, Kim, Mee Kyoung, Sohn, Tae-Seo, Baek, Ki-Hyun, Song, Ki-Ho, Son, Hyun-Shik, Han, Kyungdo, Kwon, Hyuk-Sang
Format: Article
Language:English
Subjects:
cardiovascular diseases
diabetes complications
ldl cholesterol
type 2 diabetes mellitus
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Summary:Objective Real-world-based population data about the optimal low-density lipoprotein cholesterol (LDL-C) level for preventing cardiovascular disease in very high-risk populations is scarce. Methods From 2009 to 2012, 26,922 people aged ≥ 40 years with type 2 diabetes mellitus (T2DM) who had a history of percutaneous coronary intervention (PCI) were analyzed. Data from the Korean National Health Insurance System were used. They were followed up to the date of a cardiovascular event or the time to death, or until December 31, 2018. Endpoints were recurrent PCI, newly stroke or heart failure, cardiovascular death, and all-cause death. Participants were divided into the following categories according to LDL-C level:
ISSN:2049-3614
2049-3614
DOI:10.1530/EC-23-0142