Blood and faecal lead levels in children with various functional gastrointestinal disorders

Introduction: To investigate the blood lead levels (BLLs) and faecal lead levels (FLLs) in children with various functional gastrointestinal disorders (FGIDs) and compare them with controls. Patients and methods: One hundred and two children with FGIDs defined by the Rome IV criteria, aged 4–18 year...

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Bibliographic Details
Published in:Anales de Pediatría 2022-01, Vol.96 (1), p.35-42
Main Authors: Nergiz Sevinc, Namık Bilici, Eylem Sevinc, Erkan Dogan
Format: Article
Language:Spanish
Subjects:
Niveles de plomo en heces
Niveles de plomo en sangre
Niños
Trastornos gastrointestinales funcionales
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Summary:Introduction: To investigate the blood lead levels (BLLs) and faecal lead levels (FLLs) in children with various functional gastrointestinal disorders (FGIDs) and compare them with controls. Patients and methods: One hundred and two children with FGIDs defined by the Rome IV criteria, aged 4–18 years, and one hundred and two sex matched healthy children were enrolled in the study. Children with FGIDs were divided into three subgroups as functional constipation (FC) (n = 36), functional abdominal pain (FAP) (n = 36) and functional nausea (FN) (n = 30). The lead levels were measured using atomic absorption spectrometer. Results: The median BLLs in the FGIDs group was significantly higher than in controls (5.12 and 1.77 µg/dL, respectively). The BLLs were above 5 µg/dL in 51,9% of children with FGIDs. There was statistically significant difference in BLLs between FC subgroup and the other subgroups (FAP and FN) (p = 0.003, p 
ISSN:2341-2879
2341-2879