Probiotics, Prebiotics, and Synbiotics in the Irritable Bowel Syndrome Treatment: A Review

Irritable bowel syndrome is not a life-threatening disease, yet it significantly affects the quality of life and contributes to economic loss. It is estimated that even up to 45% of the world’s population can suffer from the disease. The first attempts to diagnose irritable bowel syndrome were made...

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Bibliographic Details
Published in:Biomolecules (Basel, Switzerland) Switzerland), 2021-08, Vol.11 (8), p.1154
Main Authors: Chlebicz-Wójcik, Agnieszka, Śliżewska, Katarzyna
Format: Article
Language:English
Subjects:
Abdomen
Colon
Constipation
Defecation
Diarrhea
Disease
Etiology
Food
Inflammatory bowel disease
Intestinal microflora
Intestine
Irritable bowel syndrome
Microbiota
Microorganisms
Motility
Nervous system
Pain
Prebiotics
Probiotics
Quality of life
Review
synbiotics
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Summary:Irritable bowel syndrome is not a life-threatening disease, yet it significantly affects the quality of life and contributes to economic loss. It is estimated that even up to 45% of the world’s population can suffer from the disease. The first attempts to diagnose irritable bowel syndrome were made at the end of the 19th century; however, establishing appropriate diagnostic criteria and treatment methods is still ongoing. To date, little is known about the etiology of irritable bowel syndrome; however, growing attention is drawn to the intestinal microbiota as a factor in the disease development. For this reason, researchers have conducted many studies on therapies that modulate the microbiota, among which probiotics, prebiotics, and synbiotics are widely studied. To date, most studies have examined probiotics; however, there are also several studies demonstrating the efficacy of prebiotics and synbiotics. The aim of this review was to summarize findings on the usefulness of probiotics, prebiotics, and synbiotics in the treatment of irritable bowel syndrome.
ISSN:2218-273X
2218-273X
DOI:10.3390/biom11081154