Midterm outcome after en bloc resection of C2 chordoma with transoral mandibular split and mesh cage reconstruction: a case report

• Published in: Journal of medical case reports 2023-06, Vol.17 (1), p.229-229, Article 229
• Main Authors: Korwutthikulrangsri, Ekkapoj, Ongard, Sunun, Pisutbenya, Jirachai, Ruangchainikom, Monchai, Sutipornpalangkul, Werasak
• Format: Article
• Language: English
• Subjects: Airway management; Care and treatment; Case Report; Case reports; Chordoma; Dissection; En bloc resection; Fiberoptic endoscopic evaluation of swallowing; Hospitals; Magnetic resonance imaging; Mandibular split; Medical equipment and supplies industry; Medical imaging; Medical prognosis; Medical test kit industry; Mouth; Navigation systems; Ostomy; Spinal cord; Surgeons; Surgery; Sutures; Tomography; Tongue; Tracheostomy; Tracheotomy; Tumors, Embryonal; Upper cervical spine; Veins & arteries
• ISSN: 1752-1947; 1752-1947
• DOI: 10.1186/s13256-023-03958-2

Chordomas are rare, locally aggressive tumors that often occur in the axial spine, especially in the sacrum. The treatment of chordomas located in the upper cervical spine is challenging. En bloc resection is the preferred surgical option for total tumor removal. We report the case of a C2 chordoma in a 47-year-old Thai woman. She was treated with a two-stage, anterior-posterior, C2 total spondylectomy with titanium mesh cage reconstruction and radiotherapy. The first stage involved posterior stabilization from the occiput to C5, a total laminectomy, and removal of the posterior rings of the bilateral foramen transversarium to preserve the bilateral vertebral arteries. The second stage comprised a transoral mandibular split with en bloc resection of C2, followed by titanium mesh cage reconstruction and kick-off anterior cervical plating. At the 5 year follow-up, no tumor recurrence was identified on magnetic resonance imaging. The patient had no neurological deficits but still had minor complications from the anterior transoral mandibular split. Excellent midterm results were obtained using a transoral mandibular split with reconstruction and posterior spinal fusion from the occiput to the lower cervical spine coupled with adjuvant radiotherapy. We recommend this approach as the treatment of choice for chordoma in the upper cervical spine.