Concomitant preoperative airflow obstruction confers worse prognosis after trans-thoracic surgery for esophageal cancer

Airflow obstruction is a critical element of chronic airway diseases. This study aimed to evaluate the impact of preoperative airflow obstruction on the prognosis of patients following surgery for esophageal carcinoma. A total of 821 esophageal cancer patients were included and classified into two g...

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Bibliographic Details
Published in:Frontiers in surgery 2023-01, Vol.9, p.966340-966340
Main Authors: Lang, Ke, Wang, Xiaocen, Wei, Tingting, Gu, Zhaolin, Song, Yansha, Yang, Dong, Wang, Hao
Format: Article
Language:English
Subjects:
airflow obstruction
decision-making
esophageal cancer
lung function
Surgery
survival
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Summary:Airflow obstruction is a critical element of chronic airway diseases. This study aimed to evaluate the impact of preoperative airflow obstruction on the prognosis of patients following surgery for esophageal carcinoma. A total of 821 esophageal cancer patients were included and classified into two groups based on whether or not they had preoperative airflow obstruction. Airflow obstruction was defined as a forced expiration volume in the first second (FEV )/forced vital capacity (FVC) ratio below the lower limit of normal (LLN). A retrospective analysis of the impact of airflow obstruction on the survival of patients with esophageal carcinoma undergoing esophagectomy was performed. Patients with airflow obstruction (102/821, 12.4%) had lower three-year overall (42/102, 58.8%) and progression-free survival rate (47/102, 53.9%) than those without airflow obstruction (
ISSN:2296-875X
2296-875X
DOI:10.3389/fsurg.2022.966340