Serum leptin, atherogenic lipids and glucose levels in patients with skin tags

To investigate the relationship between serum leptin, atherogenic lipid and glucose levels in patients with skin tags and healthy controls. A total of 58 patients, with at least three skin tags, aged 24 to 85 years, and 31 healthy controls aged 30 to 70 years, were examined in the present study. The...

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Bibliographic Details
Published in:Indian journal of dermatology 2009, Vol.54 (1), p.20-22
Main Authors: Gorpelioglu, Canan, Erdal, Emel, Ardicoglu, Yasemin, Adam, Bahattin, Sarifakioglu, Evren
Format: Article
Language:English
Subjects:
Atherogenic lipid
Blood sugar
Body mass index
Diabetes
Diagnosis
Diet
Insulin resistance
Leptin
Lipids
Measurement
Nutrition
Original
Physiological aspects
Regression analysis
Rodents
Skin
Skin diseases
skin tags
Studies
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Summary:To investigate the relationship between serum leptin, atherogenic lipid and glucose levels in patients with skin tags and healthy controls. A total of 58 patients, with at least three skin tags, aged 24 to 85 years, and 31 healthy controls aged 30 to 70 years, were examined in the present study. The subjects in all the groups were selected with statistically similar Body Mass Index (BMI). Fasting concentrations of plasma glucose, serum lipids including triglyceride, total cholesterol, and high-density lipoprotein cholesterol (HDL) and low-density lipoprotein cholesterol (LDL), HbA1c, and leptin were measured by enzyme-linked immunosorbent assay (ELISA). In addition, serum LDL level was calculated using Friedewald's formula. There was no significant difference in age, sex, BMI, HbA1c, triglyceride, HDL and leptin levels between the groups. Skin tags group showed significantly higher levels of total cholesterol and LDL, when compared with the healthy controls groups (P < 0.01). In addition, regression analysis showed that leptin level was positively correlated to serum triglyceride level (r = 0.265, P = 0.044). Total cholesterol and LDL serum levels should be controlled in patients with skin tags. On the other hand, glucose, leptin and HbA1c serum levels may not be as important as is being considered in recent times.
ISSN:0019-5154
1998-3611
DOI:10.4103/0019-5154.48980