Intramedullary craniovertebral junction tuberculoma: An uncommon location of a common disease

Summary Central nervous system involvement is observed in no more than 10% of patients with systemic tuberculosis. Although CNS tuberculosis is not rare in endemic countries, such as India, intramedullary tuberculosis is not commonly reported. In this study, we report a case of a 40-year-old female...

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Bibliographic Details
Published in:Journal of infection and public health 2014-07, Vol.7 (4), p.365-368
Main Authors: Jain, Rajendra S, Handa, Rahul, Srivastava, Trilochan, Prakash, Swayam, Nagpal, Kadam, Bhana, Indu, Gupta, Pankaj K
Format: Article
Language:English
Subjects:
Adult
Anti-Inflammatory Agents - therapeutic use
Antitubercular Agents - therapeutic use
Bacterial diseases
Biological and medical sciences
Craniovertebral junction
Female
Human bacterial diseases
Humans
India
Infectious Disease
Infectious diseases
Internal Medicine
Intramedullary
Magnetic Resonance Imaging
Medical sciences
Quadriplegia - diagnosis
Quadriplegia - etiology
Radiography
Spinal Cord - diagnostic imaging
Spinal Cord Diseases - complications
Spinal Cord Diseases - diagnosis
Spinal Cord Diseases - drug therapy
Spinal Cord Diseases - pathology
Treatment Outcome
Tuberculoma
Tuberculoma - complications
Tuberculoma - diagnosis
Tuberculoma - drug therapy
Tuberculoma - pathology
Tuberculosis and atypical mycobacterial infections
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Summary:Summary Central nervous system involvement is observed in no more than 10% of patients with systemic tuberculosis. Although CNS tuberculosis is not rare in endemic countries, such as India, intramedullary tuberculosis is not commonly reported. In this study, we report a case of a 40-year-old female who presented with a six-year history of insidious onset, gradually progressive, asymmetric quadriparesis. She was diagnosed with intramedullary tuberculoma at the craniovertebral junction and showed significant clinico-radiological improvement with medical management alone. To the best of our knowledge, this report describes the first case of intramedullary tuberculoma at the craniovertebral junction to be reported. With the increased availability of MRI in developing countries, it is now possible for clinicians to diagnose this condition without performing a biopsy. It is important for the clinicians in developed countries to be highly suspicious of intramedullary tuberculoma, as there has been a resurgence of CNS tuberculosis due to the emergence of the HIV pandemic.
ISSN:1876-0341
1876-035X
DOI:10.1016/j.jiph.2014.04.006