Harnessing the antibacterial activity of Quercus infectoria and Phyllanthus emblica against antibiotic-resistant Salmonella Typhi and Salmonella Enteritidis of poultry origin

In a scenario of the ineffectiveness of the current drugs against antibiotic-resistant pathogens, the herbal extracts can serve as an alternative remedy. This study appraises the antibacterial potency of (gall), (fruit) individually and synergistically against antimicrobial-resistant (AMR) Typhi and...

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Bibliographic Details
Published in:Veterinary World 2020-07, Vol.13 (7), p.1388-1396
Main Authors: Nair, Amruta, Balasaravanan, T, Jadhav, Sunil, Mohan, Vysakh, Kumar, Chethan
Format: Article
Language:English
Subjects:
Antibacterial activity
Antibacterial agents
Antibiotic resistance
Antibiotics
antimicrobial-resistant
Drug resistance
Flavonoids
Gas chromatography
gas chromatography-mass spectrometry
Mass spectroscopy
Phyllanthus emblica
phytochemicals
Plant extracts
Poultry
Quercus infectoria
Salmonella
Salmonella Enteritidis
Salmonella Typhi
Saponins
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Summary:In a scenario of the ineffectiveness of the current drugs against antibiotic-resistant pathogens, the herbal extracts can serve as an alternative remedy. This study appraises the antibacterial potency of (gall), (fruit) individually and synergistically against antimicrobial-resistant (AMR) Typhi and Enteritidis in a time and dose-dependent manner. Further, the antibacterial phytocompounds were identified employing gas chromatography-mass spectrometry (GC-MS). Preliminary antibacterial activity of the plant extracts was assessed using the agar disk diffusion method. evaluations of methanolic extract (QIME) and methanolic extract (PEME) against . Typhi and . Enteritidis were carried out using plate count method. QIME and PEME at a dose rate of 50 mg/ml and 25 mg/ml, respectively, had a complete bactericidal effect on AMR . Typhi and . Enteritidis whereas 10 log CFU/ml of exponential growth was seen in untreated control groups. At the lower concentrations, QIME and PEME had a significant bacteriostatic effect (3-6 log reduction of the test isolates). The synergistic antibacterial effect obtained from the combination of these two plant extracts at 12.5 mg/ml was superior (p
ISSN:0972-8988
2231-0916
DOI:10.14202/vetworld.2020.1388-1396