Utility of Saline-Induced Resting Full-Cycle Ratio Compared with Resting Full-Cycle Ratio and Fractional Flow Reserve

Background. The saline-induced distal coronary pressure/aortic pressure ratio predicted fractional flow reserve (FFR). The resting full-cycle ratio (RFR) represents the maximal relative pressure difference in a cardiac cycle. Therefore, the present study aimed to compare the results of saline-induce...

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Bibliographic Details
Published in:Journal of interventional cardiology 2020, Vol.2020 (2020), p.1-7
Main Authors: Aizawa, Yoshifusa, Takahashi, Minoru, Yuasa, Sho, Taya, Yuji, Ohta, Yusuke, Goto, Sonoka, Sato, Takao, Okabe, Masaaki
Format: Article
Language:English
Subjects:
Acute coronary syndromes
Adenosine
Aged
Aged, 80 and over
Agreements
Angioplasty
Aorta
Arterial Pressure - physiology
Cardiac arrhythmia
Cardiac Catheterization
Cardiovascular disease
Catheters
Coronary Angiography
Coronary artery
Coronary Stenosis - diagnosis
Coronary Stenosis - physiopathology
Coronary vessels
Coronary Vessels - physiopathology
Female
Fractional Flow Reserve, Myocardial - physiology
Heart beat
Hemodynamics
Humans
Intravenous administration
Ischemia
Lesions
Male
Medical imaging
Middle Aged
Predictive Value of Tests
Pressure
ROC Curve
Sensitivity and Specificity
Severity of Illness Index
Stenosis
Stents
Values
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Summary:Background. The saline-induced distal coronary pressure/aortic pressure ratio predicted fractional flow reserve (FFR). The resting full-cycle ratio (RFR) represents the maximal relative pressure difference in a cardiac cycle. Therefore, the present study aimed to compare the results of saline-induced RFR (sRFR) with FFR. Methods. Seventy consecutive lesions with only moderate stenosis were included. The FFR, RFR, and sRFR values were compared. The sRFR was assessed using an intracoronary bolus infusion of saline (2 mL/s) for five heartbeats. The FFR was obtained after an intravenous injection of papaverine. Results. Overall, the FFR, sRFR, and RFR values were 0.78 ± 0.12, 0.79 ± 0.13, and 0.83 ± 0.14, respectively. With regard to anatomical morphology were 40, 18, and 12 cases of focal, diffuse, and tandem lesion. There was a significant correlation between the sRFR and FFR (R = 0.96, p
ISSN:0896-4327
1540-8183
DOI:10.1155/2020/5787439