Cardiac implantable electronic devices (CIEDs) and allergy

Advances in cardiac implantable electronic devices (CIEDs) have prolonged life expectancy in various medical settings. However, the issue of hypersensitivity to components of CIEDs is still a concern. Since 1970, allergic reactions to metallic and nonmetallic components of CIEDs have been reported....

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Bibliographic Details
Published in:Journal of arrhythmia 2023-06, Vol.39 (3), p.310-314
Main Authors: De Ruvo, Ermenegildo, Petrungaro, Mattia, De Luca, Lucia, Bressi, Edoardo, Bruni, Giuseppe, Fagagnini, Alessandro, Grieco, Domenico, Martino, Anna Maria, Panuccio, Marco, Politano, Alessandro, Rebecchi, Marco, Calò, Leonardo
Format: Article
Language:English
Subjects:
Allergens
Allergic reaction
allergic reactions
Allergies
Allergy
Biological products
Bisphenol A
Blood
cardiac implantable electronic devices
Care and treatment
Clinical Review
Clinical Reviews
Defibrillators
Dermatitis
Eczema
Electrodes
Epoxy resins
Erythema
Health aspects
hypersensitivity
Implants, Artificial
Infection
Infections
Molybdenum
Nickel
Pacemakers
Patients
Prosthesis
Pruritus
Silicones
Titanium alloys
Transplants & implants
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Summary:Advances in cardiac implantable electronic devices (CIEDs) have prolonged life expectancy in various medical settings. However, the issue of hypersensitivity to components of CIEDs is still a concern. Since 1970, allergic reactions to metallic and nonmetallic components of CIEDs have been reported. Hypersensitivity reactions to medical devices are rare and not fully understood. In some cases, diagnosis and treatment are difficult. Cardiologists should always keep in mind pacemaker allergy when a patient appears with wound complications and no signs of infection. Patch testing should be tailored toward the specific biomaterials used in a device, in addition to testing with standard screening allergens in select cases. Device allergy is a rare clinical condition, probably underreported. Diagnosis and treatment can be difficult because there are no clear indications or guidelines. However, clinical suspicion should always keep in mind a device allergic reaction.
ISSN:1880-4276
1883-2148
DOI:10.1002/joa3.12852