Intravenous thrombolytic therapy for acute ischemic stroke in Hubei, China: a survey of thrombolysis rate and barriers

Rates of thrombolysis in most countries are well below best practice benchmarks. We aimed to investigate thrombolysis utilization and its associated factors in acute ischemic stroke (AIS) patients in Hubei province, China, to assess neurologists' experiences of the treatment, and to identify ba...

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Bibliographic Details
Published in:BMC neurology 2019-08, Vol.19 (1), p.202-202, Article 202
Main Authors: Zhou, Yanfeng, Yan, Shijiao, Song, Xingyue, Gong, Yanhong, Li, Wenzhen, Wang, Mengdie, Yin, Xiaoxv, Hu, Bo, Lu, Zuxun
Format: Article
Language:English
Subjects:
Benchmarking
Cardiovascular disease
Care and treatment
China
Decision making
Education
Emergency medical care
Emergency medical services
Emergency services
Family medical history
FDA approval
Hospital admission and discharge
Hospitals
Industrialized nations
Intravenous administration
Ischemia
Job titles
Medical research
Neurologists
Patient outcomes
Patients
Physicians
Practice
Questionnaires
Risk factor
Stroke
Studies
Thrombolysis
Thrombolytic drugs
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Summary:Rates of thrombolysis in most countries are well below best practice benchmarks. We aimed to investigate thrombolysis utilization and its associated factors in acute ischemic stroke (AIS) patients in Hubei province, China, to assess neurologists' experiences of the treatment, and to identify barriers against the treatment from perspective of AIS patients and neurologists. Survey of 2096 AIS patients and 709 neurologists from 66 hospitals was conducted in Hubei province between 2014 and 2015. A multivariable logistic regression model was utilized to identify the factors associated with thrombolysis utilization and neurologists' experiences with thrombolysis. Of the 2096 AIS patients, only 3.8% received thrombolysis. Of the 709 neurologists, 66.0% reported using thrombolysis for AIS patients. The main reasons for not using thrombolysis were late arrival of patients, fear of the risk of complications of thrombolysis, and light or quickly recovered stroke symptoms. The behavior and clinical characteristics of patients, including early admission to hospital (odds ratio [OR] = 5.81, 95% confidence intervals [CI] 3.31-10.20), using emergency medical services to be hospitalized (OR = 3.36, 95% CI 2.00-5.62), stroke history (OR = 0.53, 95% CI 0.28-0.99), and National Institute of Health Stroke Scale score 
ISSN:1471-2377
1471-2377
DOI:10.1186/s12883-019-1418-z