Global longitudinal strain and outcome after endoscopic mitral valve repair

Aims Identification of heart failure (HF) patients with secondary mitral regurgitation (SMR) that benefit from mitral valve (MV) repair remains challenging. We have focused on the role of left ventricular global longitudinal strain (LV‐GLS) and reservoir left atrial longitudinal strain (LASr) for th...

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Bibliographic Details
Published in:ESC Heart Failure 2022-08, Vol.9 (4), p.2686-2694
Main Authors: Kotrc, Martin, Bartunek, Jozef, Benes, Jan, Beles, Monika, Vanderheyden, Marc, Casselman, Filip, Ondrus, Tomas, Mo, Yujing, Praet, Frank Van, Penicka, Martin
Format: Article
Language:English
Subjects:
Endoscopic mitral valve repair
Endoscopy
Etiology
Hospitals
Ischemia
Medical prognosis
Mortality
Original
Reverse remodelling
Secondary mitral regurgitation
Statistical analysis
Strain
Survival
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Summary:Aims Identification of heart failure (HF) patients with secondary mitral regurgitation (SMR) that benefit from mitral valve (MV) repair remains challenging. We have focused on the role of left ventricular global longitudinal strain (LV‐GLS) and reservoir left atrial longitudinal strain (LASr) for the prediction of long‐term survival and reverse remodelling in patients with SMR undergoing endoscopic MV repair. Methods and results The study population consisted of 110 patients (age 67 ± 11 years, 66% men) with symptomatic SMR undergoing isolated MV repair using a minimally invasive surgical approach. Speckle tracking‐derived LV‐GLS and LASr were assessed in apical views using vendor‐independent software. Over a median of 7.7 years (IQRs 2.9–11.2), 64 patients (58%) died. Significant reverse LV (↓ LVESVI >10 mL/m2), LA (↓ LAVI >10 mL/m2) remodelling or both were observed in 43 (39%), 37 (34%) and 19 (17%) patients, respectively. LV‐GLS (HR 0.68, 95% CI 0.58–0.79, P 
ISSN:2055-5822
2055-5822
DOI:10.1002/ehf2.14001