Structural and functional characterization of IdeC, a novel IgG-specific protease of Streptococcus canis

is an important opportunistic pathogen of cats, dogs, and cows, which can cause a range of infections, ranging from skin and soft tissue infections to septicemia and endocarditis. As a zoonotic agent, has also recently been implicated in serious human infections, following trauma or immunosuppressio...

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Bibliographic Details
Published in:	Infection and immunity 2025-09, Vol.93 (9), p.e0024825
Main Authors:	Walsh, Saoirse, Lapschies, Antje-Maria, Miguel-Ruano, Vega, Batuecas, María T., Acebrón-Ávalos, Iván, Kohler, Thomas P., Hammerschmidt, Sven, Eichhorn, Inga, Hermoso, Juan A., Fulde, Marcus
Format:	Article
Language:	English
Subjects:	Amino Acid Sequence Animals Antibodies, Bacterial - metabolism Bacterial Proteins - chemistry Bacterial Proteins - genetics Bacterial Proteins - metabolism Cats Cysteine Proteases - chemistry Cysteine Proteases - genetics Cysteine Proteases - metabolism Dogs host pathogen interaction host specificity Humans IgG protease Immunoglobulin G Immunoglobulin G - chemistry Immunoglobulin G - metabolism Models, Molecular Molecular Pathogenesis Streptococcal Infections - immunology Streptococcal Infections - microbiology Streptococcus - enzymology Streptococcus - immunology Streptococcus canis Substrate Specificity Veterinary Microbiology
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