Prevalence and risk factors of dry eye disease in young and middle-aged office employee: a Xi'an Study

• Published in: International journal of ophthalmology 2021-04, Vol.14 (4), p.567-573
• Main Authors: Hu, Jing-Wen, Zhu, Xiu-Ping, Pan, Shi-Yin, Yang, Hua, Xiao, Xiang-Hua
• Format: Article
• Language: English
• Subjects: age; central air conditioning; dry eye disease; female; Investigation; office employee; prevalence; video display terminal
• ISSN: 2222-3959; 2227-4898
• DOI: 10.18240/ijo.2021.04.14

To estimate the prevalence of and risk factors for dry eye disease (DED) in young and middle-aged office employee in Xi'an. This cross-sectional study of the prevalence of and risk factors for DED investigated 486 young and middle-aged Chinese office employee in Xi'an. DED symptoms and potential risk factors were assessed using the ocular surface disease index combined with a risk factors questionnaire, and tear function was evaluated using the tear film break-up time and Schirmer's test. Possible risk factors for DED were estimated by binary Logistic regression analysis. DED was diagnosed in 100 females and 96 males, giving a prevalence of 40.3% [95% confidence interval (CI)=36.0%-44.7%]. The multivariate binary Logistic regression model indicated that the possible risk factors for DED were being female (OR=1.592, 95%CI=1.034-2.451, =0.035), being aged ≥40y (OR=1.593, 95%CI=1.034-2.454, =0.035), using a VDT daily for >6h (OR=1.990, 95%CI=1.334-2.971, =0.001), the presence of central air conditioning (OR=1.548, 95%CI=1.053-2.276, =0.026), and self-reported dryness of the mouth and nose (OR=1.589, 95%CI=1.071-2.357, =0.021). There is a high prevalence of clinically diagnosed DED in young and middle-aged video display terminal (VDT) users. Interventions against the modifiable risk factors should be taken to prevent the occurrence and development of DED in this population.