Optimizing inhalation therapy in the aspect of peak inhalation flow rate in patients with chronic obstructive pulmonary disease or asthma

• Published in: BMC pulmonary medicine 2021-09, Vol.21 (1), p.302-10, Article 302
• Main Authors: Hua, Jian-Lan, Ye, Xiao-Fen, Du, Chun-Ling, Xie, Ning, Zhang, Jie-Qing, Li, Man, Zhang, Jing
• Format: Article
• Language: English
• Subjects: Adult; Aged; Asthma; Asthma - drug therapy; Chronic obstructive pulmonary disease; Data collection; Drug dosages; Dry Powder Inhalers; Enrollments; Female; Hospitals; Humans; Inhalation; Inhalers; Lung diseases; Male; Middle Aged; Obstructive lung disease; Patient Education as Topic; Patients; Peak inhalation flow rate; Prospective Studies; Pulmonary Disease, Chronic Obstructive - drug therapy; Pulmonology; Respiration; Respiratory Therapy; Respiratory tract diseases; Technique training
• ISSN: 1471-2466; 1471-2466
• DOI: 10.1186/s12890-021-01674-5

Pressurized metered dose inhalers (pMDIs) and dry powder inhalers (DPIs) are commonly used drug-delivering devices for patients with chronic airway diseases. Appropriate peak inhalation flow rate (PIFR) and inhaler technique is essential for effective therapy. We aimed at optimizing inhalation therapy through the analysis of PIFRs in patients with chronic obstructive pulmonary disease (COPD) or asthma as well as the effect of technique training using In-Check DIAL® to help patients to achieve their optimal inspiratory flow rates. The study continuously enrolled patients who were diagnosed as COPD or asthma from respiratory clinics. PIFRs were described and analyzed between the newly-diagnosed and follow-up patients, and the stable and acute exacerbation patients, respectively. Every participant was trained inhaler technique using In-Check DIAL®. PIFRs before and after training was compared by self-control analysis. Among a total of 209 patients, the average age was 56.9 years. For DPIs users, 10.8% patients had a PIFR