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De novo chromophobe renal cell carcinoma in the graft three decades after renal transplantation in a patient with a history of three renal transplants

De novo renal allograft tumors were reported sporadically. Most of them were small, low-grade, and papillary renal cell carcinoma (RCC) type. A 46-year-old male presented with hematuria three decades after the first transplant. The patient had a history of three renal transplants. A tumor (12 cm × 1...

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Bibliographic Details
Published in:Saudi journal of kidney diseases and transplantation 2020-01, Vol.31 (1), p.271-275
Main Authors: Zahran, Mohamed, Soltan, Mohamed, Kamal, Ahmed, Abdelrahim, Mona, Fakhreldin, Islam, Osman, Yasser, Ali-El-Dein, Bedeir
Format: Article
Language:English
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Summary:De novo renal allograft tumors were reported sporadically. Most of them were small, low-grade, and papillary renal cell carcinoma (RCC) type. A 46-year-old male presented with hematuria three decades after the first transplant. The patient had a history of three renal transplants. A tumor (12 cm × 13 cm) was diagnosed in the nonfunctioning first transplanted kidney. Radical nephrectomy of the graft harboring the tumor with preservation of the adjacent functioning graft was done and identified to be chromophobe RCC. After two-year follow-up, the patients had a perfect graft function with no evidence of oncological failure. We suggest that allograft tumor be considered in patient evaluation for hematuria. Regular follow-up imaging of transplanted kidney is mandatory even after graft failure for early detection of graft tumors.
ISSN:1319-2442
2320-3838
DOI:10.4103/1319-2442.279952