C-H bond halogenation catalyzed or mediated by copper: an overview

Carbon-halogen (C-X) bonds are amongst the most fundamental groups in organic synthesis, they are frequently and widely employed in the synthesis of numerous organic products. The generation of a C-X bond, therefore, constitutes an issue of universal interest. Herein, the research advances on the co...

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Bibliographic Details
Published in:Beilstein journal of organic chemistry 2015-11, Vol.11 (1), p.2132-2144
Main Authors: Hao, Wenyan, Liu, Yunyun
Format: Article
Language:English
Subjects:
C(sp2)–H bond
C(sp3)–H bond
Chemistry
copper
halogenation
Review
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Summary:Carbon-halogen (C-X) bonds are amongst the most fundamental groups in organic synthesis, they are frequently and widely employed in the synthesis of numerous organic products. The generation of a C-X bond, therefore, constitutes an issue of universal interest. Herein, the research advances on the copper-catalyzed and mediated C-X (X = F, Cl, Br, I) bond formation via direct C-H bond transformation is reviewed.
ISSN:1860-5397
1860-5397
DOI:10.3762/bjoc.11.230