Establishment of hematological reference intervals for healthy adults in Asmara

Clinical laboratory reference intervals used in a specific area should be derived from the local population as they are influenced by many factors. The purpose of this quantitative cross sectional study was to establish hematological reference intervals for healthy adults in Asmara and to determine...

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Bibliographic Details
Published in:BMC research notes 2018-01, Vol.11 (1), p.55-55, Article 55
Main Authors: Siraj, Nejat, Issac, John, Anwar, Mohammed, Mehari, Yohannes, Russom, Shushan, Kahsay, Semere, Frezghi, Haben
Format: Article
Language:English
Subjects:
Anemia
Asmara
Blood
Blood levels
Blood platelets
Cell size
College students
Diagnosis
Disease
Distribution
Erythrocytes
Gender differences
Hematocrit
Hematologic diseases
Hematology
Hemoglobin
Hepatitis B
Hepatitis C
Laboratories
Males
Out of range
Quality control
Red blood cell count
Reference intervals
Research Note
Sex differences
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Summary:Clinical laboratory reference intervals used in a specific area should be derived from the local population as they are influenced by many factors. The purpose of this quantitative cross sectional study was to establish hematological reference intervals for healthy adults in Asmara and to determine whether the currently used reference interval do represent the adult population in the city. In addition, the established reference intervals were compared to findings from similar studies conducted in selected countries in Africa. There was a significant difference between males and females in the reference intervals for erythrocyte count, hemoglobin, hematocrit, mean cell volume, mean cell hemoglobin, mean cell hemoglobin concentration and differential white blood cell count. All the evaluated hematological analytes were found to be higher in males than in females except for platelet count. The out of range percentage for the parameters extends from 3.5 to 46.7%; with red blood cell count having the lowest while mean cell volume having the highest out of range percentage. The results indicated that the currently used reference interval does not represent the population in Asmara and are different from those obtained elsewhere in Africa.
ISSN:1756-0500
1756-0500
DOI:10.1186/s13104-018-3142-y