Cardiac left ventricular myocardial tissue density, evaluated by computed tomography and autopsy

Left ventricular mass (LVM) is an independent risk factor for the prediction of cardiac events. Its assessment is a clinically important diagnostic procedure in cardiology and may be performed by Computed Tomography (CT). The aim of this study was to assess the correlation between the cardiac left v...

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Bibliographic Details
Published in:BMC medical imaging 2019-04, Vol.19 (1), p.29-29, Article 29
Main Authors: Gheorghe, Alexandra G, Fuchs, Andreas, Jacobsen, Christina, Kofoed, Klaus F, Møgelvang, Rasmus, Lynnerup, Niels, Banner, Jytte
Format: Article
Language:English
Subjects:
Anatomic Left Ventricular Mass
Asymmetry
Autopsies
Autopsy
Cardiology
CAT scans
Computation
Computed Tomography
Correlation analysis
Criminal investigations
Density
Diagnostic equipment (Medical)
Diagnostic imaging
Diagnostic systems
Forensic pathology
Heart
Heart hypertrophy
Hypertrophy
Left Ventricular Mass
Left Ventricular Shell Volume
Mathematical analysis
Medical imaging
Mental disorders
Myocardial Tissue Density
NMR
Nuclear magnetic resonance
Population
Regression analysis
Risk analysis
Risk factors
Studies
Tissues
Tomography
Variability
Ventricle
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Summary:Left ventricular mass (LVM) is an independent risk factor for the prediction of cardiac events. Its assessment is a clinically important diagnostic procedure in cardiology and may be performed by Computed Tomography (CT). The aim of this study was to assess the correlation between the cardiac left ventricular shell volume (LVShV) determined by postmortem Computed Tomography (PMCT) and the anatomic LVM obtained at autopsy and to calculate the myocardial tissue density. A total of 109 deceased individuals were examined with a 64-slice CT scanner and LVShV was determined. At autopsy, the left ventricle was dissected and weighted. The correlation between LVShV and the anatomic LVM was analysed. Asymmetric left ventricular (LV) hypertrophy was recorded. Inter-observer variability was evaluated, and a density value for myocardial tissue was calculated. The mean age of the deceased was 55 ± 16 years, and 58% was men. We found 30 cases of asymmetric LV hypertrophy. A highly positive correlation existed between LVShV and anatomic LVM (r = 0.857; p 
ISSN:1471-2342
1471-2342
DOI:10.1186/s12880-019-0326-4