Early Endoscopic Intervention in Pancreaticopleural Fistula: A Single-Center Experience

• Published in: Journal of digestive endoscopy 2020-12, Vol.11 (4), p.263-269
• Main Authors: Pawar, Vinay Balasaheb, Rathi, Pravin, Thanage, Ravi, Debnath, Prasanta, Nair, Sujit, Contractor, Qais
• Format: Article
• Language: English
• Subjects: chronic pancreatitis; early endoscopic management of pancreaticopleural fistula; pancreatic ductal leak; pancreaticopleural fistula; Research Article
• ISSN: 0976-5042; 0976-5050
• DOI: 10.1055/s-0040-1721655

Abstract Background  Pancreaticopleural fistulas are among the rarest complications of chronic pancreatitis. The main objective of the research, conducted on a total of seven patients, was to evaluate the effectiveness of early endoscopic management of pancreaticopleural fistula. Methods  The diagnosis of fistula was reached when fistulous tract was demonstrated on imaging studies and/or pleural fluid amylase level was greater than 2,000 U/L. The data were retrospectively analyzed from the records. Results  The prototype patient in our series was a chronic alcoholic male with median age of 45 years. Computed tomography scan was performed in all the seven patients but could diagnose leak only in four patients. Magnetic resonance cholangiopancreatography was better in the remaining three patients for diagnosing fistula. Endoscopic retrograde cholangiopancreatography was the most sensitive test that diagnosed fistula in all the seven patients. Pancreatic duct (PD) cannulation was successful and pancreatic sphincterotomy with PD stenting was performed in all the seven patients. We could avoid surgical intervention in our patients. Conclusions  We advise early endoscopic treatment within 7 days of symptom onset as opposed to 3 weeks, which was proposed previously. Medical therapies should be complimentary to PD stenting.