The Relationship between Anemia and Helicobacter Pylori Infection in Children

(1) Background: Many studies suggest that Helicobacter pylori (H. pylori) infection is associated with a higher prevalence of anemia. The aim of this study is to explore this fact for a pediatric population from the northeast of Romania; (2) Methods: A correlational retrospective study between infec...

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Bibliographic Details
Published in:Children (Basel) 2022-08, Vol.9 (9), p.1324
Main Authors: Lupu, Ancuta, Miron, Ingrith Crenguta, Cianga, Anca Lavinia, Cernomaz, Andrei Tudor, Lupu, Vasile Valeriu, Munteanu, Dragos, Ghica, Dragos Catalin, Fotea, Silvia
Format: Article
Language:English
Subjects:
Age groups
Anemia
Biopsy
Blood platelets
children
Childrens health
Diabetes
Disease
Endoscopy
Esophagus
Gastroenterology
Helicobacter infections
Helicobacter pylori
Hemoglobin
Infections
Inflammation
Iron
iron deficiency
Lymphoma
Patients
Pediatrics
Physiological aspects
Purpura
Statistical analysis
Stomach
Ulcers
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Summary:(1) Background: Many studies suggest that Helicobacter pylori (H. pylori) infection is associated with a higher prevalence of anemia. The aim of this study is to explore this fact for a pediatric population from the northeast of Romania; (2) Methods: A correlational retrospective study between infection with H. pylori and anemia was performed on a group of 542 children in a pediatric gastroenterology regional center in Northeast Romania; (3) Results: Out of 542 children with confirmed H. pylori infection, microcytic hypochromic anemia was present in 48 children, of whom 7 (14.5%) also had iron deficiency.; (4) Conclusions: The study results demonstrate a significant association of H. pylori infection with iron-deficiency anemia and iron deficiency in children in accordance with the results established in the published literature. Although the direct relationship between them it is not clear yet, prevention represents one of the first clinical measures that need to be implemented when encountering a refractory moderate to severe iron-deficiency anemia and, especially, when associated with gastrointestinal tract symptoms.
ISSN:2227-9067
2227-9067
DOI:10.3390/children9091324