An evaluation of the mental health impact of SARS-CoV-2 on patients, general public and healthcare professionals: A systematic review and meta-analysis

Background: The global impact of COVID-19 pandemic continues to affect the lives of billions of people with recurrent waves. Healthcare systems are struggling to manage pre-existing patient care and recurring covid-19 demands. As a result, we evaluated the mental health impact using systematic revie...

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Bibliographic Details
Published in:EClinicalMedicine 2021-04, Vol.34, p.100806-100806, Article 100806
Main Authors: Phiri, Peter, Ramakrishnan, Rema, Rathod, Shanaya, Elliot, Kathryn, Thayanandan, Tony, Sandle, Natasha, Haque, Nyla, Chau, Steven W.H., Wong, Oscar W.H., Chan, Sandra S.M., Wong, Evelyn K.Y., Raymont, Vanessa, Au-Yeung, Sheena K., Kingdon, David, Delanerolle, Gayathri
Format: Article
Language:English
Subjects:
COVID-19
Health
Healthcare professionals
Mental health and physical wellbeing
Research Paper
Sars-CoV-2
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Summary:Background: The global impact of COVID-19 pandemic continues to affect the lives of billions of people with recurrent waves. Healthcare systems are struggling to manage pre-existing patient care and recurring covid-19 demands. As a result, we evaluated the mental health impact using systematic review and meta-analysis. Methods: A comprehensive search was undertaken from April 2020 to 22nd January 2021 using multiple electronic databases. A systematic review protocol was developed and published on PROSPERO registration; CRD42020181481. A random-effects model was used to compute pooled estimates of anxiety, depression, PTSD, insomnia and suicidal thoughts. Findings: Our search yielded 11,295 studies and of those 287 met the inclusion criteria. The meta-analysis of 206 studies revealed minimal differences in prevalence of anxiety, depression, and PTSD among HCPs compared with the public during the pandemic but higher prevalence of suicidal thoughts/ideation or self-harm (11% vs 5.8%) and lower prevalence of wellbeing (28.2% vs 52.6%) among the public compared to HCPs. Interpretation: The pandemic has led to a high mental health burden especially amongst HCPs and higher suicidal ideation and lower wellbeing in general public which warrants further investigation and management globally. These findings highlight an emerging critical public health issue that requires urgent solutions.
ISSN:2589-5370
2589-5370
DOI:10.1016/j.eclinm.2021.100806