Resorption characteristics of an open architecture biocomposite interference screw after ACL reconstruction

Purpose Absorbable interference screws for anterior cruciate ligament reconstruction (ACLR) can lead to tunnel widening and cyst formation. The Biosure Regenesorb interference screw (Smith & Nephew). has been developed with an optimised calcium phosphate/polymer composition to promote bone forma...

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Bibliographic Details
Published in:Journal of experimental orthopaedics 2024-10, Vol.11 (4), p.e70016-n/a
Main Authors: Lind, Martin, Nielsen, Torsten Grønbech, Nielsen, Flemming K., Sørensen, Ole G., Mygind‐Klavsen, Bjarne, Faunø, Peter
Format: Article
Language:English
Subjects:
ACL reconstruction
bone in growth
graft fixation
interference screw
Original Paper
resorbable screw
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Summary:Purpose Absorbable interference screws for anterior cruciate ligament reconstruction (ACLR) can lead to tunnel widening and cyst formation. The Biosure Regenesorb interference screw (Smith & Nephew). has been developed with an optimised calcium phosphate/polymer composition to promote bone formation during resorption. The present study aims to investigate screw resorption, new bone formation, and tunnel geometry following ACLR with Biosure Regenesorb screw tibial fixation. Methods The study is a prospective single‐centre case series of 12 patients with ACL lesions and treated with ACLR using hamstring tendon autograft with Biosure Regenesorb interference screw tibial fixation with a two‐year follow‐up period. The Biosure Regenesorb consists of 65% polylactide‐glycolic acid poly. 20% calcium sulphate and 15% tricalcium phosphate. Primary endpoint: Tunnel volume. implant volume and new bone formation in the tibial tunnel is evaluated by quantitative computed tomography (CT) scanning. Secondary endpoints: Arthrometric knee laxity, International Knee Documentation Committee (IKDC) and Knee Osteoarthritis and Injury Outcome Scores (KOOS) and Tegner activity scale. Results Screw volume decreased to 44% within the two‐year follow‐up period while tunnel volume remained unchanged. Only a minor amount (
ISSN:2197-1153
2197-1153
DOI:10.1002/jeo2.70016