Clinical analysis of 48 cases of malignant superior vena cava syndrome

Background The aim of our study was to observe and compare the curative effect of radiotherapy, chemotherapy, and combined radiotherapy and chemotherapy, as well as comprehensive treatment on superior vena cava syndrome (SVCS) caused by malignant etiology. Methods A total of 48 patients with maligna...

Full description

Saved in:
Bibliographic Details
Published in:World journal of surgical oncology 2021-06, Vol.19 (1), p.1-185, Article 185
Main Authors: Sun, Manzhen, Chen, Xiaoli, Li, Hongfei, Zhang, Xudong, Wang, Xiaofei, Zheng, Ruipan, Li, Guowen, Wang, Lin, Li, Dianyuan
Format: Article
Language:English
Subjects:
Anticoagulants
Antimitotic agents
Antineoplastic agents
Cancer
Cancer therapies
Care and treatment
Causes and theories of causation
Causes of
Chemotherapy
Complications and side effects
Comprehensive treatment
Diagnosis
Diseases
Diuretics
Edema
Esophagus
Etiology
Health services
Lung cancer
Lymphoma
Malignant etiology
Medical imaging
Medical prognosis
Patient outcomes
Patients
Quality of life
Radiation therapy
Radiotherapy
Remission (Medicine)
Side effects
Statistical analysis
Stents
Superior vena cava syndrome
Survival
Thrombosis
Tumors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background The aim of our study was to observe and compare the curative effect of radiotherapy, chemotherapy, and combined radiotherapy and chemotherapy, as well as comprehensive treatment on superior vena cava syndrome (SVCS) caused by malignant etiology. Methods A total of 48 patients with malignant SVCS admitted to our hospital from 2015 to 2020 were selected in this study. According to the different treatment methods, they were divided into radiotherapy group (group 1, 10 cases), chemotherapy group (group 2, 8 cases), combined radiotherapy and chemotherapy group (group 3, 22 cases), and comprehensive treatment group (group 4, 8 cases). Results There were no significant differences in efficacy and side effects among the four groups (all P > 0.05). Group 4 (median survival time of 36 months) could provide longer survival time than groups 1, 2, and 3 (median survival time of 10 months, 13.5 months, and 12 months, respectively). Conclusions For patients with severe symptoms or good prognosis, comprehensive treatment could be selected to improve the quality of life and prolong the survival period; for patients with mild symptoms, radiotherapy, chemotherapy, or combined radiotherapy and chemotherapy could also reduce the symptoms of SVCS and treat tumor lesions. Keywords: Superior vena cava syndrome, Malignant etiology, Radiotherapy, Chemotherapy, Comprehensive treatment
ISSN:1477-7819
1477-7819
DOI:10.1186/s12957-021-02300-8