The association of Neutrophil-to-Lymphocyte ratio with metabolic syndrome in U.S. Adults: Findings from the 1999–2018 National Health and Nutrition Examination survey

Highlights•Early identification of metabolic syndrome (MetS) is crucial; yet there is no available, cost-effective inflammatory biomarker. •We investigated the potential utility of neutrophil-to-lymphocyte ratio (NLR) as a simple, predictive biomarker for MetS. •The most effective NLR cut-off for id...

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Bibliographic Details
Published in:Journal of clinical & translational endocrinology 2025-03, Vol.39, p.100382-100382, Article 100382
Main Authors: Sarrafan-Chaharsoughi, Zahra, Sinaii, Ninet, Demidowich, Andrew P, Yanovski, Jack A
Format: Article
Language:English
Subjects:
Dyslipidemia, dysglycemia, hypertension
Endocrinology and Metabolism
Inflammation
Neutrophil to lymphocyte ratio
Predictive value
Research Paper
Risk Factors
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Summary:Highlights•Early identification of metabolic syndrome (MetS) is crucial; yet there is no available, cost-effective inflammatory biomarker. •We investigated the potential utility of neutrophil-to-lymphocyte ratio (NLR) as a simple, predictive biomarker for MetS. •The most effective NLR cut-off for identifying MetS was NLR ≥1.67, with 74.3% sensitivity and 62.3% specificity. •The ROC area for the most appropriate curve was 0.736, suggesting a moderate potential ability to discern those with MetS.
ISSN:2214-6237
2214-6237
DOI:10.1016/j.jcte.2024.100382