Nanostructured titanium regulates osseointegration via influencing macrophage polarization in the osteogenic environment

Fabricating nanostructured surface topography represents the mainstream approach to induce osteogenesis for the next-generation bone implant. In the past, the bone implant was designed to minimize host repulsive reactions in order to acquire biocompatibility. However, increasing reports indicate tha...

Full description

Saved in:

Bibliographic Details
Published in:	International journal of nanomedicine 2018-01, Vol.13, p.4029-4043
Main Authors:	Wang, Jinjin, Meng, Fanhui, Song, Wen, Jin, Jingyi, Ma, Qianli, Fei, Dongdong, Fang, Liang, Chen, Lihua, Wang, Qintao, Zhang, Yumei
Format:	Article
Language:	English
Subjects:	Animals Anti-Inflammatory Agents - metabolism Biomedical materials Bone marrow Cell Differentiation - drug effects Cell Polarity - drug effects Cytokines Cytokines - metabolism Genotype & phenotype Humidity Immune response Immunomodulation - drug effects Immunomodulators immunomodulatory effects Inflammation Inflammation Mediators - metabolism Laboratory animals macrophage polarization Macrophages Macrophages - cytology Macrophages - drug effects Male Mesenchymal Stem Cells - cytology Mesenchymal Stem Cells - drug effects Mice, Inbred C57BL Nanomaterials Nanostructures - chemistry Nanostructures - ultrastructure Nanotubes Oral diseases Original Research osseointegration Osseointegration - drug effects Osteogenesis - drug effects Penicillin Research centers Stem cells Surface Properties Titanium Titanium - pharmacology Topography Transcription factors Transplants & implants Tumor necrosis factor-TNF Wound healing
Citations:	Items that cite this one
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!