Effects of an ad libitum low-glycemic load diet on cardiovascular disease risk factors in obese young adults2

Background: The optimal nutritional approach for the prevention of cardiovascular disease among obese persons remains a topic of intense controversy. Available approaches range from conventional low-fat to very-low-carbohydrate diets. Objective: The aim of this pilot study was to evaluate the effica...

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Bibliographic Details
Published in:The American journal of clinical nutrition 2005-05, Vol.81 (5), p.976-982
Main Authors: Ebbeling, Cara B, Leidig, Michael M, Sinclair, Kelly B, Seger-Shippee, Linda G, Feldman, Henry A, Ludwig, David S
Format: Article
Language:English
Subjects:
cholesterol
dietary composition
glycemic index
glycemic load
Obesity
PAI-1
plasminogen activator inhibitor 1
triacylglycerol
weight-reducing diet
young adults
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Summary:Background: The optimal nutritional approach for the prevention of cardiovascular disease among obese persons remains a topic of intense controversy. Available approaches range from conventional low-fat to very-low-carbohydrate diets. Objective: The aim of this pilot study was to evaluate the efficacy of an ad libitum low-glycemic load diet, without strict limitation on carbohydrate intake, as an alternative to a conventional low-fat diet. Design: A randomized controlled trial compared 2 dietary treatments in obese young adults ( n = 23) over 12 mo. The experimental treatment emphasized ad libitum consumption of low-glycemic-index foods, with 45–50% of energy from carbohydrates and 30–35% from fat. The conventional treatment was restricted in energy (250–500 kcal/d deficit) and fat (
ISSN:0002-9165
DOI:10.1093/ajcn/81.5.976