Impact of hepatitis C virus infection on kidney transplant outcome

One hundred and forty kidney transplant recipients were evaluated to study the impact of hepatitis C virus (HCV) infection on patient and graft outcome. There .were 98 males arid 42 females with a mean age of 32.1 ± 13 years. The duration of follow-up ranged from 6-60 months with a mean period of 27...

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Bibliographic Details
Published in:Saudi journal of kidney diseases and transplantation 1995-04, Vol.6 (2), p.183-189
Main Authors: Ilyas, Michael, Ali, Muhammad A. M., Tahir, Sadi, al-Furayyih, Uthman I., Qunibi, Wajih Y., Chaudry, Tariq S., Subuh, Muhammad A. E., al-Mashari, Khalid
Format: Article
Language:English
Subjects:
Hepatitis C virus
Kidneys
Transplantation
التهاب الكبد سي
الفيروسات
الكلى
المرضى
المضاعفات
زرع الأعضاء
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Summary:One hundred and forty kidney transplant recipients were evaluated to study the impact of hepatitis C virus (HCV) infection on patient and graft outcome. There .were 98 males arid 42 females with a mean age of 32.1 ± 13 years. The duration of follow-up ranged from 6-60 months with a mean period of 27.8 ± 18.2 months. Seventy-four (53%) patients had received cadaveric kidneys while 66 (47%) received living donor grafts. Anti-HCV reactivity was tested using second generation enzyme-linked immunosorbent assay and positivity was confirmed by recombinant immunoblot assay. HCV infection was diagnosed in 29 cases (20.7%) while HBsAg was found in nine (6.4%) and concomitant anti-HCV and HBsAg positivity was observed in two patients (1.4%). Seventeen of 29 (58.6%) patients with anti-HCV reactivity showed elevated ALT levels as against 17 of 111 (17.3%) anti-HCV non-reactive patients (P
ISSN:1319-2442
2320-3838