The NF-κB signalling pathway in osteoarthritis

•Osteoarthritis (OA) is a degenerative disease affecting all compartments of the joint.•NF-κB signalling pathway is a major catabolic pathway in OA joints.•NF-κB triggers the expression of various genes which are implicated in cartilage destruction, synovial membrane inflammation and increased subch...

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Bibliographic Details
Published in:	The international journal of biochemistry & cell biology 2013-11, Vol.45 (11), p.2580-2584
Main Authors:	Rigoglou, Stella, Papavassiliou, Athanasios G.
Format:	Article
Language:	English
Subjects:	Animals Arrays Biocompatibility Biomedical materials Cartilage destruction chemokines Chondrocytes Cytokines Degradation evolution extracellular matrix Gene expression genes Humans Models, Biological NF-kappa B - metabolism NF-κB Osteoarthritis Osteoarthritis - metabolism Osteoarthritis - pathology Osteoarthritis - therapy pathogenesis Pathways proteins Signal Transduction Signalling transcription factor NF-kappa B
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