Development of an

Multicomponent protein complexes called inflammasomes play a major role in the innate immune system by activating proinflammatory cytokines and promoting a highly inflammatory form of programmed cell death, called pyroptosis. A hallmark of the function of the nucleotide-binding domain, leucine-rich...

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Bibliographic Details
Published in:BioTechniques 2021-06, Vol.70 (6), p.350-354
Format: Article
Language:English
Subjects:
ASC
immune response
inflammasome
innate immunity
microscale thermophoresis
polymerization
Online Access:Get full text
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