Mast Cells Expedite Control of Pulmonary Murine Cytomegalovirus Infection by Enhancing the Recruitment of Protective CD8 T Cells to the Lungs

The lungs are a noted predilection site of acute, latent, and reactivated cytomegalovirus (CMV) infections. Interstitial pneumonia is the most dreaded manifestation of CMV disease in the immunocompromised host, whereas in the immunocompetent host lung-infiltrating CD8 T cells confine the infection i...

Full description

Saved in:
Bibliographic Details
Published in:PLoS pathogens 2014-04, Vol.10 (4), p.e1004100
Main Authors: Ebert, Stefan, Becker, Marc, Lemmermann, Niels A. W., Büttner, Julia K., Michel, Anastasija, Taube, Christian, Podlech, Jürgen, Böhm, Verena, Freitag, Kirsten, Thomas, Doris, Holtappels, Rafaela, Reddehase, Matthias J., Stassen, Michael
Format: Article
Language:English
Subjects:
Animals
Biology and Life Sciences
CD8-Positive T-Lymphocytes - immunology
CD8-Positive T-Lymphocytes - pathology
Cytomegalovirus
Cytomegaloviruses
Health aspects
Herpesviridae Infections - genetics
Herpesviridae Infections - immunology
Herpesviridae Infections - pathology
Host-parasite relationships
Immune system
Lung - immunology
Lung - pathology
Lung - virology
Lung diseases
Lungs
Mast cells
Mast Cells - immunology
Mast Cells - pathology
Medical research
Medicine and Health Sciences
Mice
Mice, Mutant Strains
Microbiological research
Muromegalovirus - immunology
Muromegalovirus - metabolism
Physiological aspects
Pneumonia, Viral - genetics
Pneumonia, Viral - immunology
Pneumonia, Viral - pathology
T cells
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!