Novel Nanotechnology of Ti[O.sub.2] Improves Physical-Chemical and Biological Properties of Glass Ionomer Cement

• Published in: International journal of biomaterials 2017-01, Vol.2017
• Main Authors: Cibim, Daniela Dellosso, Saito, Miki Taketomi, Giovani, Priscila Alves, Borges, Ana Flavia Sanches, Pecorari, Vanessa Gallego Arias, Gomes, Orisson Ponce, Lisboa-Filho, Paulo Noronha, Nociti, Francisco Humberto, Jr, Puppin-Rontani, Regina Maria, Kantovitz, Kamila Rosamilia
• Format: Article
• Language: English
• Subjects: Chemical properties; Information management; Nanotechnology; Nanotubes; Powders
• ISSN: 1687-8787
• DOI: 10.1155/2017/7123919

The aim of this study was to assess the performance of glass ionomer cement (GIC) added with Ti[O.sub.2] nanotubes. Ti[O.sub.2] nanotubes [3%, 5%, and 7% (w/w)] were incorporated into GIC's (Ketac Molar EasyMix[TM]) powder component, whereas unblended powder was used as control. Physical-chemical-biological analysis included energy dispersive spectroscopy (EDS), surface roughness (SR), Knoop hardness (SH), fluoride-releasing analysis, cytotoxicity, cell morphology, and extracellular matrix (ECM) composition. Parametric or nonparametric ANOVA were used for statistical comparisons (a < 0.05). Data analysis revealed that EDS only detected Ti at the 5% and 7% groups and that GIC's physical-chemical properties were significantly improved by the addition of 5% Ti[O.sub.2] as compared to 3% and GIC alone. Furthermore, regardless of Ti[O.sub.2] concentration, no significant effect was found on SR, whereas GIC-containing 7% Ti[O.sub.2] presented decreased SH values. Fluoride release lasted longer for the 5% and 7% Ti[O.sub.2] groups, and cell morphology/spreading and ECM composition were found to be positively affected by Ti[O.sub.2] at 5%. In conclusion, in the current study, nanotechnology incorporated in GIC affected ECM composition and was important for the superior microhardness and fluoride release, suggesting its potential for higher stress-bearing site restorations.