In Vitro and In Silico Evaluation of a Novel Multifunctional Cyclic Peptide with Antioxidant, Tyrosinase-Inhibitory, and Extracellular Matrix-Modulating Activities

Peptides are notable cosmetic ingredients owing to their diverse biological activities and beneficial effects on skin health. Therefore, multifunctional peptides capable of simultaneously exerting antioxidant, whitening, and anti-wrinkle effects are highly desirable. In this study, a scalable and co...

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Bibliographic Details
Published in:	International journal of molecular sciences 2025-11, Vol.26 (22), p.10878
Main Authors:	Kim, Ga-Hyun, Kim, Bo-Mi
Format:	Article
Language:	English
Subjects:	Aging Amino acids Analysis Antioxidants Antioxidants - chemistry Antioxidants - pharmacology Biological activity Cell Survival - drug effects Chemical synthesis Collagen Commercialization Cosmetics Cytotoxicity Enzyme Inhibitors - chemistry Enzyme Inhibitors - pharmacology Extracellular matrix Extracellular Matrix - drug effects Extracellular Matrix - metabolism Health aspects Humans Ingredients Liu, Timothy Matrix Metalloproteinase 1 - metabolism Molecular Docking Simulation Molecular weight Monophenol Monooxygenase - antagonists & inhibitors Monophenol Monooxygenase - chemistry Monophenol Monooxygenase - metabolism Oxidative stress Peptides Peptides, Cyclic - chemical synthesis Peptides, Cyclic - chemistry Peptides, Cyclic - pharmacology Production costs Skin
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