A human neurodevelopmental model for Williams syndrome

A human neurodevelopmental model fills the current knowledge gap in the cellular biology of Williams syndrome and could lead to further insights into the molecular mechanism underlying the disorder and the human social brain. An iPSC model for Williams syndrome Individuals with the neurodevelopmenta...

Full description

Saved in:
Bibliographic Details
Published in:Nature (London) 2016-08, Vol.536 (7616), p.338-343
Main Authors: Chailangkarn, Thanathom, Trujillo, Cleber A., Freitas, Beatriz C., Hrvoj-Mihic, Branka, Herai, Roberto H., Yu, Diana X., Brown, Timothy T., Marchetto, Maria C., Bardy, Cedric, McHenry, Lauren, Stefanacci, Lisa, Järvinen, Anna, Searcy, Yvonne M., DeWitt, Michelle, Wong, Wenny, Lai, Philip, Ard, M. Colin, Hanson, Kari L., Romero, Sarah, Jacobs, Bob, Dale, Anders M., Dai, Li, Korenberg, Julie R., Gage, Fred H., Bellugi, Ursula, Halgren, Eric, Semendeferi, Katerina, Muotri, Alysson R.
Format: Article
Language:English
Subjects:
13/100
45/23
631/378/87
631/532/2435
692/699/375/366
96/106
Adolescent
Adult
Apoptosis
Brain - pathology
Calcium - metabolism
Cell Differentiation
Cell Shape
Cellular biology
Cellular Reprogramming
Cerebral Cortex - pathology
Chromosomes, Human, Pair 7 - genetics
Cognitive ability
Dendrites - pathology
Diagnosis
Female
Frizzled Receptors - deficiency
Frizzled Receptors - genetics
Gene expression
Genetic disorders
Haploinsufficiency - genetics
Health aspects
Humanities and Social Sciences
Humans
Induced Pluripotent Stem Cells - pathology
letter
Male
Models, Neurological
Morphology
multidisciplinary
Neural Stem Cells - pathology
Neurons
Neurons - pathology
Phenotype
Reproducibility of Results
Science
Stem cells
Synapses - pathology
Williams syndrome
Williams Syndrome - genetics
Williams Syndrome - pathology
Young Adult
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!