Practical issues encountered while determining Minimal Clinically Important Difference in Patient-Reported Outcomes

Background Using a real dataset, we highlighted several major methodological issues raised by the estimation of the Minimal Clinically Important Difference (MCID) of a Patient-Reported Outcomes instrument. We especially considered the management of missing data and the use of more than two times of...

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Bibliographic Details
Published in:Health and quality of life outcomes 2020-05, Vol.18 (1), p.156-13, Article 156
Main Authors: Woaye-Hune, Pascal, Hardouin, Jean-Benoit, Lehur, Paul-Antoine, Meurette, Guillaume, Vanier, Antoine
Format: Article
Language:English
Subjects:
Analysis
Clinical medicine
Clinical outcomes
Computer simulation
Data management
Estimates
Human health and pathology
Information management
Life Sciences
Longitudinal modeling
Medical research
Medicine
Medicine & Public Health
Methodology
Methods
Minimal clinically important difference
Minimal important difference
Missing data
Patient-reported outcomes
Patients
Quality of life
Quality of Life Research
Standard deviation
Studies
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