Impact of human immunodeficiency virus type 1 subtype on first-line antiretroviral therapy effectiveness

The effectiveness of antiretroviral treatment (ART) was compared in 416 naive patients from a French clinical cohort infected with B and non-B HIV-1 subtypes. Time to HIV viral load (VL) undetectability was calculated for each subtype group. Three other parameters were estimated 3, 6 and 12 months a...

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Bibliographic Details
Published in:Antiviral therapy 2005-01, Vol.10 (2), p.247-254
Main Authors: BOCKET, Laurence, CHERET, Antoine, MOUTON, Yves, YAZDANPANAH, Yazdan, DEUFFIC-BURBAN, Sylvie, CHOISY, Philippe, GERARD, Yann, DE LA TRIBONNIERE, Xavier, VIGET, Nathalie, AJANA, Faïzo, GOFFARD, Anne, BARIN, Francis
Format: Article
Language:English
Subjects:
Anti-HIV Agents - therapeutic use
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antiretroviral Therapy, Highly Active
Antiviral agents
Biological and medical sciences
CD4 Lymphocyte Count
CD4-Positive T-Lymphocytes - immunology
Cohort Studies
Economics and Finance
Female
France
HIV Infections - drug therapy
HIV Infections - immunology
HIV Infections - virology
HIV-1
Humanities and Social Sciences
Humans
Life Sciences
Male
Medical sciences
Pharmacology. Drug treatments
Retrospective Studies
Santé publique et épidémiologie
Species Specificity
Treatment Outcome
Viral Load
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Summary:The effectiveness of antiretroviral treatment (ART) was compared in 416 naive patients from a French clinical cohort infected with B and non-B HIV-1 subtypes. Time to HIV viral load (VL) undetectability was calculated for each subtype group. Three other parameters were estimated 3, 6 and 12 months after enrolment: clinical progression (that is, AIDS-defining events or death), changes in CD4 cell counts from baseline and proportion of patients achieving an undetectable VL (
ISSN:1359-6535
2040-2058
DOI:10.1177/135965350501000206