Orientation of N-(1-(2-chlorophenyl)-2-(2-nitrophenyl)ethyl)-4-methylbenzenesulfonamide on silver nanoparticles: SERS studies

• Published in: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy Molecular and biomolecular spectroscopy, 2014-10, Vol.131, p.261-267
• Main Authors: Anuratha, M., Jawahar, A., Umadevi, M., Sathe, V.G., Vanelle, P., Terme, T., Meenakumari, V., Milton Franklin Benial, A.
• Format: Article
• Language: English
• Subjects: Chemical Sciences; Combustion method; Hartree Fock; N-(1-(2-chlorophenyl)-2-(2-nitrophenyl)ethyl)-4-methylbenzenesulfonamide; Silver nanoparticles; Surface enhanced Raman scattering; XRD
• ISSN: 1386-1425; 1873-3557
• DOI: 10.1016/j.saa.2014.04.125

[Display omitted] •Silver nanoparticles were synthesized using a solution combustion method.•It is an fcc crystalline structure with particle size of 59mm.•The prepared silver nanoparticle is a rod like structure.•CS is adsorbed by tilted orientation on the silver surface.•HF calculations are also performed to study the vibrational features of CS. In the present study, the silver nanoparticles were synthesized using a solution combustion method with urea as fuel. The prepared silver nanoparticles show an FCC crystalline structure with particle size of 59nm. FESEM image shows the prepared silver is a rod like structure. The surface-enhanced Raman scattering (SERS) spectrum indicates that the N-(1-(2-chlorophenyl)-2-(2-nitrophenyl)ethyl)-4-methylbenzenesulfonamide (CS) molecule adsorbed on the silver nanoparticles. The spectral analysis reveals that the sulfonamide is adsorbed by tilted orientation on the silver surface. The Hatree Fock calculations were also performed to predict the vibrational motions of CS. This present investigation has been a model system to deduce the interaction of drugs with DNA.